Evidence map›Paper›PMID 30911371›Full record

ReviewCell & bioscience2019

Function and dysfunction of plasma cells in intestine.

Xue Wang, Gui-Liang Hao, Bo-Ya Wang, Chen-Chen Gao, Yue-Xiu Wang, Li-Sheng Li, Jing-Dong Xu

Open access · goldAbstract readReview
In one paragraph

Review in Cell & bioscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Elevated DUOX2 levels correlate with necrotizing enterocolitis development.Frontiers in cellular and infection microbiology · 2025
    Article
  8. Review
  9. Article
  10. American journal of physiology. Gastrointestinal and liver physiology · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. A case of Russell body gastritis with multifocal lesions.SAGE open medical case reports · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xue Wang1School of Basic Medical Sciences, Xuanwu Hospital, Beijing Capital Medical University, Beijing, 100069 China.ORCID 0000-0002-2043-0855
Gui-Liang Hao1School of Basic Medical Sciences, Xuanwu Hospital, Beijing Capital Medical University, Beijing, 100069 China.ORCID 0000-0001-7080-9786
Bo-Ya Wang2Peking University Health Science Center, Beijing, 100081 China.ORCID 0000-0003-4771-1785
Chen-Chen Gao3Department of Physiology and Pathophysiology, School of Basic Medical Science, Capital Medical University, No. 10, Xitoutiao, Youanmenwai, Fengtai District, Beijing, 100069 China.ORCID 0000-0002-3730-0272
Yue-Xiu Wang4Department of Teaching Office, International School, Capital Medical University, Beijing, 100069 China.ORCID 0000-0002-3243-3092
Li-Sheng Li5Function Platform Center, School of Basic Medical Science, Capital Medical University, Beijing, 100069 China.ORCID 0000-0002-7255-6863
Jing-Dong Xu3Department of Physiology and Pathophysiology, School of Basic Medical Science, Capital Medical University, No. 10, Xitoutiao, Youanmenwai, Fengtai District, Beijing, 100069 China.ORCID 0000-0003-4546-563X
Capital Medical University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the main player in humoral immunity, antibodies play indispensable roles in the body's immune system. Plasma cells (PCs), as antibody factories, are important contributors to humoral immunity. PCs, recognized by their unique marker CD138, are always discovered in the medullary cords of spleen and lymph nodes and in bone marrow and mucosal lymphoid tissue. This article will review the origin and differentiation of PCs, characteristics of short- and long-lived PCs, and the secretion of antibodies, such as IgA, IgM, and IgG. PCs play a crucial role in the maintenance of intestinal homeostasis using immunomodulation though complex mechanisms. Clearly, PCs play functional roles in maintaining intestinal health, but more details are needed to fully understand all the other effects of intestinal PCs.

Indexed as

AntibodyFood allergyImmunomodulationInflammatory bowel diseaseIntestinePlasma cellsTumors

Identifiers

PMID30911371
PMCPMC6417281
OpenAlexW2942796699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.