Evidence map›Paper›PMID 30911363›Full record

ArticleJournal of extracellular vesicles2019

Highlights of the mini-symposium on extracellular vesicles in inter-organismal communication, held in Munich, Germany, August 2018.

E Bielska, P R J Birch, A H Buck, C Abreu-Goodger, R W Innes, H Jin, M W Pfaffl, S Robatzek, N Regev-Rudzki, C Tisserant and 2 more

Abstract read
In one paragraph

Article in Journal of extracellular vesicles, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Extracellular vesicles in food biotechnology.Microbial biotechnology · 2021
    Article
  7. Extracellular Vesicles Released From the Skin Commensal YeastFrontiers in cellular and infection microbiology · 2020
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

E BielskaInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham, UK.ORCID 0000-0002-3138-4719
P R J BirchDivision of Plant Sciences, School of Life Science, University of Dundee (at James Hutton Institute), Dundee, UK.ORCID 0000-0002-6559-3746
A H BuckInstitute of Immunology and Infection Research and Centre for Immunity, Infection & Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-2645-7191
C Abreu-GoodgerCentro de Investigación y Estudios Avanzados del IPN (Cinvestav), Unidad de Genómica Avanzada (Langebio), Guanajuato, Mexico.ORCID 0000-0001-8302-9893
R W InnesDepartment of Biology, Indiana University, Bloomington, IN, USA.ORCID 0000-0001-9634-1413
H JinDepartment of Microbiology and Plant Pathology, Center for Plant Cell Biology, Institute for Integrative Genome Biology, University of California, Riverside, CA, USA.
M W PfafflDivision of Animal Physiology and Immunology, TUM School of Life Sciences, Weihenstephan, Technical University of Munich, Freising, Germany.ORCID 0000-0002-3192-1019
S RobatzekBiocenter, Ludwig-Maximilians University Munich, Martinsried, Germany.
N Regev-RudzkiFaculty of Biochemistry, Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
C TisserantBiocenter, Ludwig-Maximilians University Munich, Martinsried, Germany.
S WangDivision of Plant Sciences, School of Life Science, University of Dundee (at James Hutton Institute), Dundee, UK.ORCID 0000-0002-1822-6847
A WeibergBiocenter, Ludwig-Maximilians University Munich, Martinsried, Germany.ORCID 0000-0003-4300-4864

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All living organisms secrete molecules for intercellular communication. Recent research has revealed that extracellular vesicles (EVs) play an important role in inter-organismal cell-to-cell communication by transporting diverse messenger molecules, including RNA, DNA, lipids and proteins. These discoveries have raised fundamental questions regarding EV biology. How are EVs biosynthesized and loaded with messenger/cargo molecules? How are EVs secreted into the extracellular matrix? What are the EV uptake mechanisms of recipient cells? As EVs are produced by all kind of organisms, from unicellular bacteria and protists, filamentous fungi and oomycetes, to complex multicellular life forms such as plants and animals, basic research in diverse model systems is urgently needed to shed light on the multifaceted biology of EVs and their role in inter-organismal communications. To help catalyse progress in this emerging field, a mini-symposium was held in Munich, Germany in August 2018. This report highlights recent progress and major questions being pursued across a very diverse group of model systems, all united by the question of how EVs contribute to inter-organismal communication.

Indexed as

bacteriacell-to-cell communicationExtracellular vesicles (EVs)fungiinter-organismal interactionsnematodesoomycetesplantsprotistssmall RNAs

Identifiers

PMID30911363
PMCPMC6427632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.