ReviewDiabetology & metabolic syndrome2019
The relationship between mean platelet volume and diabetic retinopathy: a systematic review and meta-analysis.
Review in Diabetology & metabolic syndrome, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- The association between platelet indices and presence and severity of psoriasis: a systematic review and meta-analysis.Clinical and experimental medicine · 2023Pooled it
- Mean platelet volume and polycystic ovary syndrome: a systematic review and meta-analysis.The Journal of international medical research · 2022Pooled it
- Platelet-associated parameters in patients with psoriasis: A PRISMA-compliant systematic review and meta-analysis.Medicine · 2021Pooled it
- Association between peripheral blood biomarkers and diabetic macular edema.Acta diabetologica · 2026Article
- Association between mean platelet volume and kidney events in patients with type 2 diabetes mellitus.Journal of diabetes investigation · 2026Article
- Platelets indices clinical implications in diabetes mellitus: A broader insight.World journal of diabetes · 2025Article
- Article
- Mean Platelet Volume Is Related to Cumulative Disease Damage in Patients with Systemic Lupus Erythematosus.Life (Basel, Switzerland) · 2024Article
- Article
- Prognostic and Diagnostic Power of Delta Neutrophil Index and Mean Platelet Component in Febrile Patients with Suspected Sepsis.Biomedicines · 2023Article
- Association of Mean Platelet Volume With Vascular Complications in the Patients With Type 2 Diabetes Mellitus.Cureus · 2022Article
- Correlation between the Outcome of Vitrectomy for Proliferative Diabetic Retinopathy and Erythrocyte Hematocrit Level and Platelet Function.Journal of clinical medicine · 2022Article
- Systematic review and Meta-analysis of 26 randomized controlled clinical trials of Compound Danshen Dripping Pill for non-proliferating diabetic retinopathy.Chinese herbal medicines · 2022Article
- Platelet adhesion in type 2 diabetes: impact of plasma albumin and mean platelet volume.Thrombosis journal · 2021Article
- Is there an association between mean platelet volume and diabetic retinopathy? A case-control study.Caspian journal of internal medicine · 2021Article
- Prevalence and risk factors of diabetic retinopathy in patients with type 2 diabetes in Shanghai.International journal of ophthalmology · 2021Article
- Platelet Indices and Its Association with Microvascular Complications Among Type 2 Diabetes Mellitus Patients in Northeast Ethiopia: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- Can Platelet Count and Mean Platelet Volume be Used as Markers of Postdural Puncture Headache in Obstetric Patients?Pain research & management · 2020Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetic retinopathy (DR) is one of the most common diseases causing blindness in the world, and most patients are already in advanced stage. Recent years, many studies reported mean platelet volume (MPV) may be associated with development of DR, but there was no consistent conclusion reached.
methodsLiterature was retrieved by formally searching PubMed, Embase, Cochrane library and Scopus and by hand searching of reference lists of related articles. Finally, a total of 14 literatures included, and Review manager 5.3 and STATA 14.0 statistical software were utilized for processing.
resultsMeta-analysis showed that MPV values in DR were significantly higher than health controls [SMD (95% CI) = 0.92 (0.60-1.24)] and type 2 diabetes mellitus without diabetic retinopathy (T2DM without DR) [SMD (95% CI) = 0.36 (0.19-0.53)]. Subgroup analysis indicated that MPV level in proliferative diabetic retinopathy (PDR) patients was higher than T2DM without DR patients [SMD (95% CI) = 0.48 (0.28, 0.68)], but this difference didn't appear in non-proliferative diabetic retinopathy (NPDR).
conclusionsThe study demonstrated that increased MPV level was significant associated with the development of DR, and it might reflect the severity of DR, which could be provided to monitor development and progression of DR clinically.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.