ReviewChinese medicine2019
Application of metabolomics in viral pneumonia treatment with traditional Chinese medicine.
Review in Chinese medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Wuhu decoction combined with azithromycin for treatment ofFrontiers in pharmacology · 2024Pooled it
- Pooled it
- Efficacy and metabolomic analysis of the pneumonia compound formulation against community-acquired pneumonia: an observational controlled before-after clinical trial.BMC infectious diseases · 2025Trial
- Review
- Enhanced antioxidant and anti-Mycoplasma hyopneumoniae activities of combined Piper sarmentosum and guava leaf extracts.The Journal of veterinary medical science · 2025Article
- Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms ofInternational journal of molecular sciences · 2025Article
- Integration of Gut Microbiota, Serum Metabolomic, and Network Pharmacology to Reveal the Anti Insomnia Mechanism of Mongolian Medicine Sugemule-4 Decoction on Insomnia Model Rats.Drug design, development and therapy · 2024Article
- Baogong decoction treats endometritis in mice by regulating uterine microbiota structure and metabolites.Microbial biotechnology · 2022Article
- Does the Metabolome of Wild-likeMolecules (Basel, Switzerland) · 2022Article
- Metabolomics profile in acute respiratory distress syndrome by nuclear magnetic resonance spectroscopy in patients with community-acquired pneumonia.Respiratory research · 2022Article
- Article
- Clinical analysis of seven pediatric patients with coronavirus disease 2019 (COVID-19) in Jingzhou, Hubei, China: a retrospective study.Translational pediatrics · 2021Article
- Isolation and Identification ofFrontiers in pharmacology · 2021Article
- The mechanism and active compounds of semenFood & nutrition research · 2021Article
- Auxiliary role of mesenchymal stem cells as regenerative medicine soldiers to attenuate inflammatory processes of severe acute respiratory infections caused by COVID-19.Cell and tissue banking · 2020Review
- Article
- Clinical features of pediatric patients with coronavirus disease (COVID-19).Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020Article
- Diuretic Effect and Metabolomics Analysis of Crude and Salt-Processed Plantaginis Semen.Frontiers in pharmacology · 2020Article
- Article
- Anemoside B4 protects againstChinese medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nowadays, traditional Chinese medicines (TCMs) have been reported to provide reliable therapies for viral pneumonia, but the therapeutic mechanism remains unknown. As a systemic approach, metabolomics provides an opportunity to clarify the action mechanism of TCMs, TCM syndromes or after TCM treatment. This review aims to provide the metabolomics evidence available on TCM-based therapeutic measures against viral pneumonia. Metabolomics has been gradually applied to the efficacy evaluation of TCMs in treatment of viral pneumonia and the metabolomics analysis exhibits a systemic metabolic shift in lipid, amino acids, and energy metabolism. Currently, most studies of TCM in treatment of viral pneumonia are untargeted metabolomics and further validations on targeted metabolomics should be carried out together with molecular biology technologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.