Evidence map›Paper›PMID 30911313›Full record

ArticleJournal of contemporary brachytherapy2019

Comparative analysis of image-guided adaptive interstitial brachytherapy and intensity-modulated arc therapy versus conventional treatment techniques in cervical cancer using biological dose summation.

Georgina Fröhlich, Júlia Vízkeleti, Anhhong Nhung Nguyen, Tibor Major, Csaba Polgár

Open access · goldAbstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Automated EQDJournal of contemporary brachytherapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Georgina FröhlichCentre of Radiotherapy, National Institute of Oncology, Budapest, Hungary.
Júlia VízkeletiCentre of Radiotherapy, National Institute of Oncology, Budapest, Hungary.
Anhhong Nhung NguyenCentre of Radiotherapy, National Institute of Oncology, Budapest, Hungary.
Tibor MajorCentre of Radiotherapy, National Institute of Oncology, Budapest, Hungary.
Csaba PolgárCentre of Radiotherapy, National Institute of Oncology, Budapest, Hungary.
National Institute of Oncology · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare image-guided adaptive interstitial brachytherapy (BT) and intensity-modulated arc therapy (IMAT) with conventional treatment techniques in cervical cancer using an alternative biological dose summation method. MATERIAL AND

methodsInitially, 21 interstitial BT and IMAT plans of patients with cervical cancer were included and additional plans were created (inverse optimized interstitial, optimized intracavitary, non-optimized intracavitary BT plans, and conformal external beam radiotherapy [EBRT]). The most exposed volume of critical organs in BT were identified manually on EBRT CT images. Biological total doses (EQD2) were calculated and compared between each combination of BT and EBRT plans. This method was compared with uniform dose conception (UDC) in IMAT and conformal EBRT plans.

resultsThe D

conclusionsAlthough optimization improves the quality of conventional BT plans, interstitial plans produce significantly higher dose coverage of high-risk clinical target volume (HR-CTV) and lower doses to organs at risk (OARs). IMAT plans decrease the dose to the rectum. UDC overestimates OARs doses.

Indexed as

cervical cancerdose summationintegrated biological dosesintensity-modulated arc therapyinterstitial brachytherapy

Identifiers

PMID30911313
PMCPMC6431106
OpenAlexW2891790604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.