Evidence map›Paper›PMID 30911309›Full record

ArticleJournal of contemporary brachytherapy2019

Changes in magnetic resonance T2-weighted imaging signal intensity correlate with concurrent chemoradiotherapy response in cervical cancer.

Bing Liu, Wan-Ling Ma, Guang-Wen Zhang, Zhen Sun, Jin-Man Zhong, Meng-Qi Wei, Hua Yang, Li-Chun Wei, Yi Huan

Open access · goldAbstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Bing LiuDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an.
Wan-Ling MaDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an.
Guang-Wen ZhangDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an.
Zhen SunDepartment of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an.
Jin-Man ZhongDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an.
Meng-Qi WeiDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an.
Hua YangDepartment of Radiation Oncology, Xijing Hospital, Fourth Military Medical University, Xi'an, P. R. China.
Li-Chun WeiDepartment of Radiation Oncology, Xijing Hospital, Fourth Military Medical University, Xi'an, P. R. China.
Yi HuanDepartment of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an.
Xijing Hospital · CNAir Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study is aimed to compare magnetic resonance imaging (MRI) parameters and clinical pathological factors (CPF) of residual tumor group with non-residual tumor group in cervical cancer (CC) patients during concurrent chemoradiotherapy (CCRT), and thus to establish a biomarker for individualized treatment strategy. MATERIAL AND

methodsFrom May 2014 to November 2015, 164 CC patients were included in this retrospective study. T2-weighted MRI was performed at pre-treatment (week-0), the completion of external radiotherapy (RT) (week-4), and one month after the completion of CCRT, using 3.0T MR scanner with regular pelvic coil. Mean signal intensity and tumor size on T

resultsThe residual tumor group showed a higher Δ tumor-to-disc signal intensity ratio (ΔTDR) than non-residual tumor group (0.78 ± 0.30 vs. 0.48 ± 0.19,

conclusionsMRI parameter ΔTDR may be an independent prognostic factor for predicting residual tumor occurrence in CC after CCRT treatment. The combination of MRI parameter and CPF can serve as a valuable biomarker to distinguish CC with higher possibility of residual tumor occurrence.

Indexed as

cervical cancerconcurrent chemoradiotherapymagnetic resonance imagingsignal intensitytreatment response

Identifiers

PMID30911309
PMCPMC6431108
OpenAlexW2923938079

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.