Evidence map›Paper›PMID 30911286›Full record

ArticleCancer cell international2019

A

Jie Mei, Ting Yan, Yifu Huang, Tiansong Xia, Fei Chang, Shuning Shen, Leiyu Hao, Yin Chen, Zhongyuan Wang, Xiaozheng Jiang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancer cell international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. The prognostic value of DAAM2 in lower grade glioma, liver cancer, and breast cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Association ofPharmacogenomics and personalized medicine · 2021
    Article
  16. Tivantinib Hampers the Proliferation of Glioblastoma Cells via PI3K/Akt/Mammalian Target of Rapamycin (mTOR) Signaling.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jie Mei *1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Ting Yan *2Safety Assessment and Research Center for Drug, Pesticide and Veterinary Drug of Jiangsu Province, Nanjing Medical University, Nanjing, 211166 China.
Yifu Huang1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Tiansong Xia4Breast Disease Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210036 China.
Fei Chang1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Shuning Shen1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Leiyu Hao1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Yin Chen1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Zhongyuan Wang1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Xiaozheng Jiang1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Bujie Xu1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Yichao Zhu1Department of Physiology, Nanjing Medical University, 101 Longmian Road, Nanjing, 211166 China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDishevelled-associated activator of morphogenesis 1 (DAAM1) is a member of microfilament-related formins and mediates cell motility in breast cancer (BrCa). However, the genetic mutation status of

methodsA patient cohort and BrCa cells were recruited to demonstrate the role of functional SNP in microRNA-208a-5p binding site of

resultsThe expression and activation of DAAM1 increased markedly in lymphnode metastatic tissues. A genetic variant (rs79036859 A/G) was validated in the miR-208a-5p binding site of

conclusionOverall, the rs79036859 G variant of

Indexed as

3′-UTRDAAM1MetastasismiR-208a-5prs79036859

Identifiers

PMID30911286
PMCPMC6417246
OpenAlexW2942345727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.