Evidence map›Paper›PMID 30911279›Full record

ReviewInternational journal of medical sciences2019

Papillary Thyroid Cancer: Genetic Alterations and Molecular Biomarker Investigations.

Mardiaty Iryani Abdullah, Sarni Mat Junit, Khoon Leong Ng, Jaime Jacqueline Jayapalan, Barani Karikalan, Onn Haji Hashim

Open access · goldAbstract readReview
In one paragraph

Review in International journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 189 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
189citing papers in PubMed, 1 pooled it
25.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

189 citing papers in PubMed, 1 synthesis or guideline pooled it, 350 citations in OpenAlex.

  1. Pooled it
  2. Identification and assessment ofOncology letters · 2026
    Article
  3. NAT10-mediated acJournal of molecular histology · 2026
    Article
  4. A Comparison of Detection Rates Between Ultrasound and Post-Therapeutic I-131 SPECT/CT for Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Construction and application of a nomogram model for early stage central lymph node metastasis in papillary thyroid cancer combined with Hashimoto's thyroiditis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  12. Review
  13. Papillary thyroid carcinoma in thyroglossal duct cyst: a Peruvian case series.Endocrinology, diabetes & metabolism case reports · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Homologous Recombination in Thyroid Tumor Samples.International journal of molecular sciences · 2025
    Article
  20. Review

129 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mardiaty Iryani AbdullahDepartment of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Sarni Mat JunitDepartment of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Khoon Leong NgDepartment of Surgery, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Jaime Jacqueline JayapalanUniversity of Malaya Centre for Proteomics Research, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Barani KarikalanPerdana University, Jalan MAEPS Perdana, Serdang 43400, Selangor, Malaysia.
Onn Haji HashimDepartment of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
University of Malaya · MYInternational Islamic University Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is usually contained within the thyroid gland and generally biologically indolent. Prognosis of the cancer is excellent, with less than 2% mortality at 5 years. However, more than 25% of patients with PTC developed a recurrence during a long term follow-up. The present article provides an updated condensed overview of PTC, which focuses mainly on the molecular alterations involved and recent biomarker investigations.

Indexed as

Biomarkers, TumorFemaleGoiter, NodularHumansMaleMicroRNAsNeoplasm Recurrence, LocalProteomicsProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-retras ProteinsThyroid Cancer, PapillaryThyroid NeoplasmsBiomarkers, TumorBRAF protein, humanMicroRNAsProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-retras ProteinsRET protein, humanbiomarkerdiagnosticsgenetic signaturemolecular alterationpapillary thyroid cancer

Identifiers

PMID30911279
PMCPMC6428975
OpenAlexW2922772115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.