ArticleNature neuroscience2019
Grid cell co-activity patterns during sleep reflect spatial overlap of grid fields during active behaviors.
Article in Nature neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed.
- Symmetries and continuous attractors in disordered neural circuits.Nature neuroscience · 2026Article
- A Two-Dimensional Grid-Cell Code for Three-Dimensional Navigation in Freely Flying Bats.bioRxiv : the preprint server for biology · 2026Article
- Flexible neural representations of abstract structural knowledge in the human entorhinal cortex.eLife · 2026Article
- Sparsification and decorrelation of granule cell activity in the dentate gyrus by noradrenaline.Communications biology · 2026Article
- Slow synaptic plasticity from the hippocampus underlies gradual mapping and fragmentation of novel spaces by grid cells.bioRxiv : the preprint server for biology · 2025Article
- Grid cells accurately track movement during path integration-based navigation despite switching reference frames.Nature neuroscience · 2025Article
- Article
- Article
- Robust variability of grid cell properties within individual grid modules enhances encoding of local space.eLife · 2025Article
- Article
- Robust variability of grid cell properties within individual grid modules enhances encoding of local space.bioRxiv : the preprint server for biology · 2024Article
- A cellular basis for mapping behavioural structure.Nature · 2024Article
- Article
- Isolated theta waves originating from the midline thalamus trigger memory reactivation during NREM sleep in mice.Nature communications · 2024Article
- Mental navigation in the primate entorhinal cortex.Nature · 2024Article
- Remapping revisited: how the hippocampus represents different spaces.Nature reviews. Neuroscience · 2024Review
- A consistent map in the medial entorhinal cortex supports spatial memory.Nature communications · 2024Article
- Abnormal patterns of sleep and waking behaviors are accompanied by neocortical oscillation disturbances in an Ank3 mouse model of epilepsy-bipolar disorder comorbidity.Translational psychiatry · 2023Article
- Ketamine evoked disruption of entorhinal and hippocampal spatial maps.Nature communications · 2023Article
- A consistent map in the medial entorhinal cortex supports spatial memory.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Continuous-attractor network models of grid formation posit that recurrent connectivity between grid cells controls their patterns of co-activation. Grid cells from a common module exhibit stable offsets in their periodic spatial tuning curves across environments, and this may reflect recurrent connectivity or correlated sensory inputs. Here we explore whether cell-cell relationships predicted by attractor models persist during sleep states in which spatially informative sensory inputs are absent. We recorded ensembles of grid cells in superficial layers of medial entorhinal cortex during active exploratory behaviors and overnight sleep. Per grid cell pair and collectively, and across waking, rapid eye movement sleep and non-rapid eye movement sleep, we found preserved patterns of spike-time correlations that reflected the spatial tuning offsets between these grid cells during active exploration. The preservation of cell-cell relationships across waking and sleep states was not explained by theta oscillations or activity in hippocampal subregion CA1. These results indicate that recurrent connectivity within the grid cell network drives grid cell activity across behavioral states.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.