Evidence map›Paper›PMID 30911146›Full record

ArticleNature ecology & evolution2019

Epistatic mutations under divergent selection govern phenotypic variation in the crow hybrid zone.

Ulrich Knief, Christen M Bossu, Nicola Saino, Bengt Hansson, Jelmer Poelstra, Nagarjun Vijay, Matthias Weissensteiner, Jochen B W Wolf

Abstract read
In one paragraph

Article in Nature ecology & evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
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  6. Widespread variation inbioRxiv : the preprint server for biology · 2025
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  8. Article
  9. Review
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  16. Spatial Overlap and Habitat Selection of Corvid Species in European Cities.Animals : an open access journal from MDPI · 2023
    Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ulrich KniefDivision of Evolutionary Biology, Faculty of Biology, LMU Munich, Munich, Germany.ORCID http://orcid.org/0000-0001-6959-3033
Christen M BossuScience for Life Laboratories and Department of Evolutionary Biology, Uppsala University, Uppsala, Sweden.
Nicola SainoDepartment of Environmental Science and Policy, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0002-0230-3967
Bengt HanssonDepartment of Biology, Lund University, Lund, Sweden.ORCID http://orcid.org/0000-0001-6694-8169
Jelmer PoelstraScience for Life Laboratories and Department of Evolutionary Biology, Uppsala University, Uppsala, Sweden.
Nagarjun VijayScience for Life Laboratories and Department of Evolutionary Biology, Uppsala University, Uppsala, Sweden.
Matthias WeissensteinerDivision of Evolutionary Biology, Faculty of Biology, LMU Munich, Munich, Germany.
Jochen B W WolfDivision of Evolutionary Biology, Faculty of Biology, LMU Munich, Munich, Germany. j.wolf@biologie.uni-muenchen.de.ORCID http://orcid.org/0000-0002-2958-5183

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The evolution of genetic barriers opposing interspecific gene flow is key to the origin of new species. Drawing from information on over 400 admixed genomes sourced from replicate transects across the European hybrid zone between all-black carrion crows and grey-coated hooded crows, we decipher the interplay between phenotypic divergence and selection at the molecular level. Over 68% of plumage variation was explained by epistasis between the gene NDP and a ~2.8-megabase region on chromosome 18 with suppressed recombination. Both pigmentation loci showed evidence for divergent selection resisting introgression. This study reveals how few, large-effect loci can govern prezygotic isolation and shield phenotypic divergence from gene flow.

Indexed as

Biological Variation, PopulationGenetic VariationAnimalsCrowsEpistasis, GeneticGene FlowHybridization, GeneticMutationPhenotype

Identifiers

PMID30911146
PMCPMC6445362

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.