Evidence map›Paper›PMID 30911064›Full record

ArticlePediatric research2019

Comparison of fetal growth by maternal prenatal acetaminophen use.

Melissa M Smarr, Joe Bible, Nicole Gerlanc, Germaine M Buck Louis, Alaina Bever, Katherine L Grantz

Open access · bronzeAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Pediatric research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Chinese Fetal Growth: A Multicenter Cohort Study Based on Fetal Ultrasound Measurements.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Melissa M SmarrDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA. melissa.smarr@emory.edu.ORCID http://orcid.org/0000-0002-4347-405X
Joe BibleSchool of Mathematical and Statistical Sciences, Clemson University, Clemson, SC, USA.
Nicole GerlancThe Prospective Group, Arlington, VA, USA.
Germaine M Buck LouisDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
Alaina BeverDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
Katherine L GrantzDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USClemson University · USEmory University · USGeorge Mason University · US

Funding

Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI William Michael Caudle · 2013 to 2026
$22.6M
NICHD NIH HHS HHSN275200800002CNICHD NIH HHS HHSN275200800002INICHD NIH HHS HHSN275200800003CNICHD NIH HHS HHSN275200800003INICHD NIH HHS HHSN275200800012CNICHD NIH HHS HHSN275200800013CNICHD NIH HHS HHSN275200800014CNICHD NIH HHS HHSN275200800028CNICHD NIH HHS HHSN275201000009CNIEHS NIH HHS P30 ES019776
6 · The paper itself

Abstract

backgroundEquivocal findings exist regarding prenatal acetaminophen use and various adverse neonatal and childhood health outcomes, though with no data on fetal growth. We evaluated whether fetal growth differed by maternal acetaminophen use.

methodsRacially diverse, healthy women with low-risk antenatal profiles from 12 US clinical centers were enrolled in a prospective cohort study and followed until delivery. Ultrasound measurements of fetal parameters and self-reported prenatal acetaminophen use were collected at enrollment and up to five follow-up visits. Prenatal acetaminophen use was dichotomized as none or any.

resultsAmong 2291 women, 932 (41%) reported the use of acetaminophen medications during the current pregnancy. Estimated growth curves of fetal parameters did not differ between women reporting use of any medication containing acetaminophen and women with no reported use of the same.

conclusionAmong healthy mothers with low-risk pregnancies, maternal acetaminophen use was not associated with alterations in fetal growth.

Indexed as

Maternal ExposureAcetaminophenAdultAnti-Inflammatory Agents, Non-SteroidalBiometryBody Mass IndexFemaleFetal DevelopmentGestational AgeHumansInfant, NewbornMaternal AgeMothersPregnancyPregnancy ComplicationsProspective StudiesAcetaminophenAnti-Inflammatory Agents, Non-Steroidal

Identifiers

PMID30911064
PMCPMC6658344
OpenAlexW2924381731

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.