ArticleScientific reports2019
Minimally-verbal children with autism show deficits in theta and gamma oscillations during processing of semantically-related visual information.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06352372 (Safety and Efficacy of Transcranial Photobiomodulation), which is not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Transcranial Photobiomodulation (tPBM) for Individuals With Autism Spectrum Disorder and Epileptiform Activity
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Impaired behavioral inhibition in Fmr1 KO mice is linked to disrupted visual cortex theta oscillations.Cell reports · 2026Article
- Theta Power at 10 Months of Age Predicts Developmental Change in Language in Infants With and Without an Elevated Likelihood for Autism.Developmental science · 2026Article
- Altered aperiodic EEG spectral power during speech perception task is associated with verbal communication in youths with Autism Spectrum Disorder.bioRxiv : the preprint server for biology · 2025Article
- A Multimodal Framework for Understanding Perceptual Segmentation of Natural Scenes In Autism.bioRxiv : the preprint server for biology · 2025Article
- Auditory evoked delta brushes involve stimulus-specific cortical networks in preterm infants.iScience · 2025Article
- The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives.Molecular autism · 2024Article
- Transcranial photobiomodulation in children aged 2-6 years: a randomized sham-controlled clinical trial assessing safety, efficacy, and impact on autism spectrum disorder symptoms and brain electrophysiology.Frontiers in neurology · 2024Article
- Predicting Communication Skills Outcomes for Preschool Children with Autism Spectrum Disorder Following Early Intervention.Neuropsychiatric disease and treatment · 2024Article
- Article
- Language in autism: domains, profiles and co-occurring conditions.Journal of neural transmission (Vienna, Austria : 1996) · 2023Review
- EEG based functional brain networks analysis in dyslexic children during arithmetic task.Cognitive neurodynamics · 2022Article
- Parental Language Input Predicts Neuroscillatory Patterns Associated with Language Development in Toddlers at Risk of Autism.Journal of autism and developmental disorders · 2022Article
- Sex differences in neuronal systems function and behaviour: beyond a single diagnosis in autism spectrum disorders.Translational psychiatry · 2021Review
- EEG/ERP as a pragmatic method to expand the reach of infant-toddler neuroimaging in HBCD: Promises and challenges.Developmental cognitive neuroscience · 2021Review
- Update about "minimally verbal" children with autism spectrum disorder.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2021Review
- Psychophysiological and Eye-Tracking Markers of Speech and Language Processing in Neurodevelopmental Disorders: New Options for Difficult-to-Test Populations.American journal on intellectual and developmental disabilities · 2020Review
- Use of longitudinal EEG measures in estimating language development in infants with and without familial risk for autism spectrum disorder.Neurobiology of language (Cambridge, Mass.) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To acquire language, children must build phonemic representations of their native language, learn to associate auditory words to visual objects and assemble a lexicon. It is not clear however, whether the limited linguistic ability seen in minimally-verbal (MV) children with Autism Spectrum Disorder (ASD) relates to deficits in cortical representation of an object and/or in linking an object to its semantic information. This EEG-based study investigated neural mechanisms underlying visual processing of common objects in MV-ASD and control children. Ten MV-ASD children, 4- to 7- years-old and 15 age/gender-matched controls, were presented with a picture-word matching paradigm. Time-frequency analyses were conducted at the sources generating the event-related responses at both early and late visual processing. Permutation testing identified spectral power and phase coherence clusters that significantly differed between the groups. As compared to controls, MV-ASD children exhibited smaller amplitudes and longer source latencies; decreased gamma and theta power with less theta phase coherence in occipital regions, and reduced frontal gamma power. Our results confirm that visual processing is altered in MV-ASD children and suggest that some of the linguistic differences observed in these children arise from impaired object/label cortical representations and reduced allocation of attention, which would impact lexical acquisition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.