Evidence map›Paper›PMID 30910982›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Structural comparison of the vacuolar and Golgi V-ATPases from

Thamiya Vasanthakumar, Stephanie A Bueler, Di Wu, Victoria Beilsten-Edmands, Carol V Robinson, John L Rubinstein

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. Article
  3. Cryo-EM single-particle analysis expanding towards increasingly native samples.Acta crystallographica. Section D, Structural biology · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Structure of ATP synthase from an early photosynthetic bacteriumProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Structure of yeast RAVE bound to a partial VProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Eukaryotic yeast VFrontiers in molecular biosciences · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Structural and Functional Diversity of Two ATP-Driven Plant Proton Pumps.International journal of molecular sciences · 2023
    Review
  19. Structural basis of V-ATPase VProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Thamiya VasanthakumarMolecular Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Stephanie A BuelerMolecular Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
Di WuPhysical and Theoretical Chemistry Laboratory, University of Oxford, OX1 3QZ Oxford, United Kingdom.
Victoria Beilsten-EdmandsPhysical and Theoretical Chemistry Laboratory, University of Oxford, OX1 3QZ Oxford, United Kingdom.
Carol V RobinsonPhysical and Theoretical Chemistry Laboratory, University of Oxford, OX1 3QZ Oxford, United Kingdom.ORCID 0000-0001-7829-5505
John L RubinsteinMolecular Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; john.rubinstein@utoronto.ca.
University of Oxford · GBUniversity of Toronto · CAHospital for Sick Children · CA

Funding

CIHR MOP81294Wellcome TrustWellcome Trust 104633/Z/14/Z
6 · The paper itself

Abstract

Proton-translocating vacuolar-type ATPases (V-ATPases) are necessary for numerous processes in eukaryotic cells, including receptor-mediated endocytosis, protein maturation, and lysosomal acidification. In mammals, V-ATPase subunit isoforms are differentially targeted to various intracellular compartments or tissues, but how these subunit isoforms influence enzyme activity is not clear. In the yeast

Indexed as

cryo-EMmembrane proteinSTV1V-ATPaseVPH1

Identifiers

PMID30910982
PMCPMC6462096
OpenAlexW2925022309

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.