ArticleProceedings of the National Academy of Sciences of the United States of America2019
Feed-forward information and zero-lag synchronization in the sensory thalamocortical circuit are modulated during stimulus perception.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Review
- Transcranial Focused Ultrasound Modulates Feedforward and Feedback Cortico-Thalamo-Cortical Pathways by Selectively Activating Excitatory Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- The quantum-classical complexity of consciousness and orchestrated objective reduction.Frontiers in human neuroscience · 2025Article
- Thalamocortical interactions shape hierarchical neural variability during stimulus perception.iScience · 2024Article
- A Consolidated Understanding of the Contribution of Redox Dysregulation in the Development of Hearing Impairment.Antioxidants (Basel, Switzerland) · 2024Review
- Intracortical microstimulation of human somatosensory cortex is sufficient to induce perceptual biases.medRxiv : the preprint server for health sciences · 2024Article
- Thalamocortical loops as temporal demodulators across senses.Communications biology · 2023Review
- Hemodynamic transient and functional connectivity follow structural connectivity and cell type over the brain hierarchy.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Computational methods to study information processing in neural circuits.Computational and structural biotechnology journal · 2023Review
- Hierarchical unimodal processing within the primary somatosensory cortex during a bimodal detection task.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Disentangling the flow of signals between populations of neurons.Nature computational science · 2022Article
- Statistical methods for dissecting interactions between brain areas.Current opinion in neurobiology · 2020Review
- Inferring neural information flow from spiking data.Computational and structural biotechnology journal · 2020Review
- Intracortical microstimulation of human somatosensory cortex induces natural perceptual biases.Brain stimulationArticle
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Authors and funding
7 authors.
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Abstract
The direction of functional information flow in the sensory thalamocortical circuit may play a role in stimulus perception, but, surprisingly, this process is poorly understood. We addressed this problem by evaluating a directional information measure between simultaneously recorded neurons from somatosensory thalamus (ventral posterolateral nucleus, VPL) and somatosensory cortex (S1) sharing the same cutaneous receptive field while monkeys judged the presence or absence of a tactile stimulus. During stimulus presence, feed-forward information (VPL → S1) increased as a function of the stimulus amplitude, while pure feed-back information (S1 → VPL) was unaffected. In parallel, zero-lag interaction emerged with increasing stimulus amplitude, reflecting externally driven thalamocortical synchronization during stimulus processing. Furthermore, VPL → S1 information decreased during error trials. Also, VPL → S1 and zero-lag interaction decreased when monkeys were not required to report the stimulus presence. These findings provide evidence that both the direction of information flow and the instant synchronization in the sensory thalamocortical circuit play a role in stimulus perception.
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