Evidence map›Paper›PMID 30910970›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Dual actions of group B

Satoshi Uchiyama, Josh Sun, Kyoko Fukahori, Nao Ando, Mengyou Wu, Flavio Schwarz, Shoib S Siddiqui, Ajit Varki, Jamey D Marth, Victor Nizet

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 80 citations in OpenAlex.

  1. Antibacterial Activity of Rosmarinic Acid AgainstAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Review
  4. mBio · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Matrine AttenuatesMicroorganisms · 2025
    Article
  9. Article
  10. Identification of glyoxalase A in group BInfection and immunity · 2025
    Article
  11. Identification of Glyoxalase A in Group BbioRxiv : the preprint server for biology · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Biofilm-dispersed pneumococci induce elevated leukocyte and platelet activation.Frontiers in cellular and infection microbiology · 2024
    Article
  17. Review
  18. Capsule production promotes Group BMicrobiology spectrum · 2023
    Article
  19. Article
  20. The Role of Clinical Glyco(proteo)mics in Precision Medicine.Molecular & cellular proteomics : MCP · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Satoshi UchiyamaDepartment of Pediatrics, University of California, San Diego, La Jolla, CA 92093; sauchiyama@ucsd.edu vnizet@ucsd.edu.
Josh SunDepartment of Pediatrics, University of California, San Diego, La Jolla, CA 92093.
Kyoko FukahoriDepartment of Pediatrics, University of California, San Diego, La Jolla, CA 92093.
Nao AndoDepartment of Pediatrics, University of California, San Diego, La Jolla, CA 92093.
Mengyou WuDepartment of Pediatrics, University of California, San Diego, La Jolla, CA 92093.
Flavio SchwarzDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Shoib S SiddiquiDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.
Ajit VarkiDepartment of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093.ORCID 0000-0002-2206-975X
Jamey D MarthCenter for Nanomedicine, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037.
Victor NizetDepartment of Pediatrics, University of California, San Diego, La Jolla, CA 92093; sauchiyama@ucsd.edu vnizet@ucsd.edu.ORCID 0000-0003-3847-0422
University of California San Diego · USUniversity of California, Santa Barbara · US

Funding

Protein Glycosylation in the Coagulopathy and Inflammation of SepsisP01HL131474 · NHLBI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI ESKO, JEFFREY D · 2016 to 2025
$26.2M
Siglec Modulation of Inflammatory ResponsesP01HL107150 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LE, DZUNG T · 2011 to 2017
$18.0M
GLYCOSYLTRANSFERASE FUNCTION IN DEVELOPMENT AND DISEASER01DK048247 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JAMEY MARTH · 1994 to 2026
$9.4M
Cathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6M
Glycoprotein Remodeling in the Vasculopathy and Coagulopathy of SepsisR01HL125352 · NHLBI · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI MARTH, JAMEY, NIZET, VICTOR · 2014 to 2018
$3.6M
NHLBI NIH HHS P01 HL107150NHLBI NIH HHS P01 HL131474NHLBI NIH HHS R01 HL125352NIAID NIH HHS R37 AI052453NIDDK NIH HHS R01 DK048247
6 · The paper itself

Abstract

Circulating platelets have important functions in thrombosis and in modulating immune and inflammatory responses. However, the role of platelets in innate immunity to bacterial infection is largely unexplored. While human platelets rapidly kill

Indexed as

Platelet ActivationStreptococcus agalactiaeAdultAnimalsAntigens, CDAntigens, Differentiation, B-LymphocyteBacterial CapsulesBlood Bactericidal ActivityBlood PlateletsFemaleGlycocalyxHumansMaleMiceMice, KnockoutN-Acetylneuraminic AcidAntigens, CDAntigens, Differentiation, B-LymphocyteN-Acetylneuraminic AcidSialic Acid Binding Immunoglobulin-like LectinsSIGLEC9 protein, humanSiglece protein, mouseVirulence Factorsgroup B Streptococcusinnate immunityplateletssialic acidSiglec

Identifiers

PMID30910970
PMCPMC6462088
OpenAlexW2924118954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.