Evidence map›Paper›PMID 30910896›Full record

ArticleAntimicrobial agents and chemotherapy2019

Andrew T Nishimoto, Nathan P Wiederhold, Stephanie A Flowers, Qing Zhang, Steven L Kelly, Joachim Morschhäuser, Christopher M Yates, William J Hoekstra, Robert J Schotzinger, Edward P Garvey and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
  2. Review
  3. Drug Discovery and Repurposing forJournal of fungi (Basel, Switzerland) · 2025
    Review
  4. Review
  5. Review
  6. Antifungal Drug Resistance.Current topics in microbiology and immunology · 2025
    Review
  7. Review
  8. Review
  9. Fungal lung disease.The European respiratory journal · 2024
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. New trends in antifungal treatment: What is coming up?Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Andrew T NishimotoUniversity of Tennessee Health Science Center, Memphis, Tennessee, USA.
Nathan P WiederholdUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-2225-5122
Stephanie A FlowersUniversity of Tennessee Health Science Center, Memphis, Tennessee, USA.
Qing ZhangUniversity of Tennessee Health Science Center, Memphis, Tennessee, USA.
Steven L KellySwansea University, Swansea, Wales, United Kingdom.
Joachim MorschhäuserUniversität Würzburg, Würzburg, Germany.
Christopher M YatesViamet Pharmaceuticals, Inc., Durham, North Carolina, USA.
William J HoekstraViamet Pharmaceuticals, Inc., Durham, North Carolina, USA.
Robert J SchotzingerViamet Pharmaceuticals, Inc., Durham, North Carolina, USA.
Edward P GarveyViamet Pharmaceuticals, Inc., Durham, North Carolina, USA.
P David RogersUniversity of Tennessee Health Science Center, Memphis, Tennessee, USA drogers@uthsc.edu.
University of Tennessee Health Science Center · USViamet Pharmaceuticals (United States) · USSwansea University · GBThe University of Texas Health Science Center at San Antonio · USUniversity of Würzburg · DE

Funding

Novel Azole Resistance Mechanisms in Candida albicansR01AI058145 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ROGERS, P. DAVID · 2005 to 2021
$5.8M
NIAID NIH HHS R01 AI058145
6 · The paper itself

Abstract

The fungal Cyp51-specific inhibitors VT-1161 and VT-1598 have emerged as promising new therapies to combat fungal infections, including

Indexed as

Antifungal AgentsAzolesCandida albicansDrug Resistance, FungalFluconazoleFungal ProteinsHumansMicrobial Sensitivity TestsMutationPyridinesTetrazolesTranscription FactorsAntifungal AgentsAzolesFluconazoleFungal ProteinsPyridinesTetrazolesTranscription FactorsVT-1161VT-1598antifungal resistanceantifungal susceptibility testingazole resistanceCandida albicanstetrazole

Identifiers

PMID30910896
PMCPMC6535515
OpenAlexW2924845564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.