Evidence map›Paper›PMID 30910860›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

Skin Wounding-Induced Monocyte Expansion in Mice Is Not Abrogated by IL-1 Receptor 1 Deficiency.

Pijus K Barman, Jingbo Pang, Norifumi Urao, Timothy J Koh

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Obesity Disrupts H3K4me3-Mediated Lactate Accumulation and Efferocytosis in Hypoxic Macrophages.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Macrophages as a therapeutic target to promote diabetic wound healing.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Review
  6. Review
  7. Review
  8. Macrophage-mediated inflammation in diabetic wound repair.Seminars in cell & developmental biology · 2021
    Review
  9. Review
  10. Review
  11. Article
  12. Macrophage Dysregulation and Impaired Skin Wound Healing in Diabetes.Frontiers in cell and developmental biology · 2020
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pijus K BarmanCenter for Wound Healing and Tissue Regeneration, Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612.
Jingbo PangCenter for Wound Healing and Tissue Regeneration, Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612.
Norifumi UraoCenter for Wound Healing and Tissue Regeneration, Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612.ORCID 0000-0001-9750-8406
Timothy J KohCenter for Wound Healing and Tissue Regeneration, Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612 tjkoh@uic.edu.ORCID 0000-0001-6549-7060
University of Illinois Chicago · US

Funding

Macrophage Phenotype and Impaired Wound HealingR01GM092850 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KOH, TIMOTHY J · 2011 to 2019
$3.5M
Impact of hematopoietic stem progenitor cell dysfunction on tissue recovery from ischemic injury in metabolic syndromeR01DK111489 · NIDDK · UPSTATE MEDICAL UNIVERSITY · PI URAO, NORIFUMI · 2017 to 2021
$2.0M
NIDDK NIH HHS R01 DK111489NIGMS NIH HHS R01 GM092850
6 · The paper itself

Abstract

The aim of this study was to determine whether skin wounding induces monocyte (Mo) expansion in bone marrow and whether IL-1R1 signaling regulates this process. Our data show that skin wounding increases myeloid lineage-committed multipotent progenitors (MPP3 subset) and Mo in bone marrow, but this expansion is not impaired in Il1r1

Indexed as

AnimalsBone MarrowMiceMice, KnockoutMonocytesReceptors, Interleukin-1 Type ISignal TransductionSkinWound HealingWounds and InjuriesIL1R1 protein, mouseReceptors, Interleukin-1 Type I

Identifiers

PMID30910860
PMCPMC6478552
OpenAlexW2941947053

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.