Evidence map›Paper›PMID 30910839›Full record

ArticleBioscience reports2019

Down-regulation of DANCR acts as a potential biomarker for papillary thyroid cancer diagnosis.

Ke Zhang, Jing Lv, Xiaowei Peng, Jianqiu Liu, Cuilin Li, Jing Li, Ningwei Yin, Hui Li, Zhi Li

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Expression ofMolecular medicine reports · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Long Non-coding RNA DANCR in Cancer: Roles, Mechanisms, and Implications.Frontiers in cell and developmental biology · 2021
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. DANCR: an emerging therapeutic target for cancer.American journal of translational research · 2020
    Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ke ZhangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, 87 Xinagya Road, Changsha 410008, P.R. China.
Jing LvDepartment of Thyroid Surgery, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou 450007, P.R. China.
Xiaowei PengDepartment of Head and Neck Surgery, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, P.R. China.
Jianqiu LiuDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, 87 Xinagya Road, Changsha 410008, P.R. China.
Cuilin LiDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, 87 Xinagya Road, Changsha 410008, P.R. China.
Jing LiDepartment of Endocrinology, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou 450007, P.R. China.
Ningwei YinDepartment of Surgery, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou 450007, P.R. China.
Hui LiNational Clinical Research Center for Geriatric Disorders, 87 Xiangya Road, Changsha 410008, Hunan, P.R. China.
Zhi LiDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, 87 Xinagya Road, Changsha 410008, P.R. China.ORCID 0000-0002-6793-9560
Central South University · CNZhengzhou Central Hospital · CNNational Clinical Research Center for Digestive Diseases · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) have been reported to be dysregulated and play a crucial role in the progression of cancer. LncRNA DANCR has recently been revealed to be involved in tumorigenesis of numerous types of cancer, including osteosarcoma, gastric cancer, breast cancer, hepatocellular carcinoma, and colorectal cancer. However, the expression profiles and biological relevance of DANCR in papillary thyroid cancer (PTC) have not yet been reported. In the present study, the expression level of DANCR in PTC tissues and adjacent normal tissues was detected by reverse transcription-quantitative PCR in PTC patients, and then we analyzed the association with clinical pathological characteristics of patients and DANCR expressions. These results demonstrated that the expression of DANCR was notably decreased in tumor tissues in comparison with adjacent normal tissues (

Indexed as

Down-RegulationGene Expression Regulation, NeoplasticAdultBiomarkers, TumorFemaleHumansMaleMiddle AgedPrognosisRNA, Long NoncodingThyroid Cancer, PapillaryThyroid NeoplasmsBiomarkers, TumorDANCR long noncoding RNA, humanRNA, Long NoncodingDANCRdiagnosislarge intervening non-coding RNAthyroid cancer

Identifiers

PMID30910839
PMCPMC6470405
OpenAlexW2937442229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.