Evidence map›Paper›PMID 30910825›Full record

ArticleDevelopment (Cambridge, England)2019

Epigenetic inactivation of miR-203 as a key step in neural crest epithelial-to-mesenchymal transition.

Estefanía Sánchez-Vásquez, Marianne E Bronner, Pablo H Strobl-Mazzulla

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Core microRNAs regulate neural crest delamination and condensation in the developing trigeminal ganglion.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
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  12. Chaotic activation of developmental signalling pathways drives idiopathic pulmonary fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  13. Post-transcriptional tuning of FGF signaling mediates neural crest induction.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Estefanía Sánchez-VásquezLaboratory of Developmental Biology, Instituto Tecnológico de Chascomús (CONICET-UNSAM), Chascomús 7130, Argentina.
Marianne E BronnerDivision of Biology 139-74, California Institute of Technology, Pasadena, CA 91125, USA.
Pablo H Strobl-MazzullaLaboratory of Developmental Biology, Instituto Tecnológico de Chascomús (CONICET-UNSAM), Chascomús 7130, Argentina strobl@intech.gov.ar.ORCID 0000-0003-0591-6168
Consejo Nacional de Investigaciones Científicas y Técnicas · ARCalifornia Institute of Technology · US

Funding

Epigenetic-miRNA circuitry directing neural crest EMT/MET to form sensory gangliaR21TW011224 · FIC · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI BRONNER, MARIANNE, STROBL MAZZULLA, PABLO HERNAN · 2018 to 2019
$419k
FIC NIH HHS R21 TW011224
6 · The paper itself

Abstract

miR-203 is a tumor-suppressor microRNA with known functions in cancer metastasis. Here, we explore its normal developmental role in the context of neural crest development. During the epithelial-to-mesenchymal transition of neural crest cells to emigrate from the neural tube, miR-203 displays a reciprocal expression pattern with key regulators of neural crest delamination,

Indexed as

AnimalsChick EmbryoEpigenomicsEpithelial-Mesenchymal TransitionGene Expression Regulation, DevelopmentalIn Situ HybridizationNeural CrestTranscription FactorsTranscription FactorsDNA methylationEMTMigrationmiR-203Neural crestPhf12Snail2

Identifiers

PMID30910825
PMCPMC6467475
OpenAlexW2950292854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.