Evidence map›Paper›PMID 30910813›Full record

ArticleThe Journal of biological chemistry2019

Yeast mitochondrial protein Pet111p binds directly to two distinct targets in

Julia L Jones, Katharina B Hofmann, Andrew T Cowan, Dmitry Temiakov, Patrick Cramer, Michael Anikin

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Julia L JonesFrom the Graduate Program in Cell and Molecular Biology, Graduate School of Biomedical Sciences and.
Katharina B Hofmannthe Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany, and.ORCID 0000-0002-0683-6277
Andrew T Cowanthe Department of Cell Biology & Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, New Jersey 08084.
Dmitry Temiakovthe Department of Biochemistry & Molecular Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Patrick Cramerthe Department of Molecular Biology, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany, and.
Michael Anikinthe Department of Cell Biology & Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, New Jersey 08084, anikinmi@rowan.edu.
Rowan University · USMax Planck Institute for Biophysical Chemistry · DEThomas Jefferson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genes in mitochondrial DNA code for essential subunits of the respiratory chain complexes. In yeast, expression of mitochondrial genes is controlled by a group of gene-specific translational activators encoded in the nucleus. These factors appear to be part of a regulatory system that enables concerted expression of the necessary genes from both nuclear and mitochondrial genomes to produce functional respiratory complexes. Many of the translational activators are believed to act on the 5'-untranslated regions of target mRNAs, but the molecular mechanisms involved in this regulation remain obscure. In this study, we used a combination of

Indexed as

Protein BiosynthesisCyclooxygenase 2Membrane ProteinsMitochondriaMitochondrial ProteinsPeptide Initiation FactorsProtein BindingRecombinant ProteinsRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCyclooxygenase 2Membrane ProteinsMitochondrial ProteinsPeptide Initiation FactorsPET111 protein, S cerevisiaeRecombinant ProteinsRNA, MessengerSaccharomyces cerevisiae Proteinscytochrome c oxidase (Complex IV)gene expressionmitochondriaPAR-CLIPpentatricopeptide repeat (PPR) proteinrespiratory complexRNA–protein interactiontranslational activatortranslation regulation

Identifiers

PMID30910813
PMCPMC6509481
OpenAlexW2923366706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.