Evidence map›Paper›PMID 30910801›Full record

ArticleThe Biochemical journal2019

Calcium-calmodulin gating of a pH-insensitive isoform of connexin43 gap junctions.

Siyu Wei, Christian Cassara, Xianming Lin, Richard D Veenstra

Open access · greenAbstract read
In one paragraph

Article in The Biochemical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Development of an HInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. CaInternational journal of molecular sciences · 2023
    Article
  6. Review
  7. Article
  8. Peptidic Connexin43 Therapeutics in Cardiac Reparative Medicine.Journal of cardiovascular development and disease · 2021
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Calmodulin-Mediated Regulation of Gap Junction Channels.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Siyu WeiDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, U.S.A.
Christian CassaraDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, U.S.A.
Xianming LinLeon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, NY 10016, U.S.A.
Richard D VeenstraDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, U.S.A. veenstrr@upstate.edu.ORCID 0000-0002-2968-3947
SUNY Upstate Medical University · USNew York University · US

Funding

GAP JUNCTIONS AND IONIC CURRENTS IN DEVELOPING HEARTR01HL042220 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI VEENSTRA, RICHARD DAVID, YANG, JENNY J. · 1988 to 2013
$3.1M
NHLBI NIH HHS R01 HL042220
6 · The paper itself

Abstract

Intracellular protons and calcium ions are two major chemical factors that regulate connexin43 (Cx43) gap junction communication and the synergism or antagonism between pH and Ca

Indexed as

Amino Acid SubstitutionAnimalsCalciumCalcium SignalingCalmodulinCell LineConnexin 43Gap JunctionsHydrogen-Ion ConcentrationIn Vitro TechniquesIon Channel GatingMiceMice, Inbred C57BLMice, Mutant StrainsMolecular MimicryMutagenesis, Site-DirectedCalciumCalmodulinConnexin 43GJA1 protein, mousecalmodulinconnexinsgap junctionsintracellular calcium

Identifiers

PMID30910801
PMCPMC12404149
OpenAlexW2935993538

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.