ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019
Heightened Defensive Responses Following Subtotal Lesions of Macaque Orbitofrontal Cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Behavioral change: from neurobiology to behavioral-change theories and back - part 1.Arquivos de neuro-psiquiatria · 2026Review
- Longitudinal Characterization of GiantResearch (Washington, D.C.) · 2026Article
- Insights into the Neurobiology of Behavioral Inhibition from Nonhuman Primate Models.Current topics in behavioral neurosciences · 2025Review
- A Study of Spontaneous Self-Injurious Behavior and Neuroimaging in Rhesus Macaques.Research (Washington, D.C.) · 2025Article
- Understanding the heterogeneity of anxiety using a translational neuroscience approach.Cognitive, affective & behavioral neuroscience · 2024Review
- Understanding anxiety symptoms as aberrant defensive responding along the threat imminence continuum.Neuroscience and biobehavioral reviews · 2023Review
- Prefrontal influences on the function of the neural circuitry underlying anxious temperament in primates.Oxford open neuroscience · 2023Article
- Threat vigilance and intrinsic amygdala connectivity.Human brain mapping · 2022Article
- Differential Effects of the Inactivation of Anterior and Posterior Orbitofrontal Cortex on Affective Responses to Proximal and Distal Threat, and Reward Anticipation in the Common Marmoset.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Social housing status impacts rhesus monkeys' affective responding in classic threat processing tasks.Scientific reports · 2022Article
- Prefrontal cortex interactions with the amygdala in primates.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- A social affective neuroscience lens on placebo analgesia.Trends in cognitive sciences · 2021Review
- Piecing together the orbitofrontal puzzle.Behavioral neuroscience · 2021Article
- A novel social fear conditioning procedure alters social behavior and mTOR signaling in differentially housed adolescent rats.Developmental psychobiology · 2021Article
- Effects of childhood trauma experience and COMT Val158Met polymorphism on brain connectivity in a multimodal MRI study.Brain and behavior · 2020Article
- Dysregulation of behavioral and autonomic responses to emotional and social stimuli following bidirectional pharmacological manipulation of the basolateral amygdala in macaques.Neuropharmacology · 2020Article
- Ventromedial prefrontal area 14 provides opposing regulation of threat and reward-elicited responses in the common marmoset.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Damage to Orbitofrontal Areas 12 and 13, but Not Area 14, Results in Blunted Attention and Arousal to Socioemotional Stimuli in Rhesus Macaques.Frontiers in behavioral neuroscience · 2020Article
- Lesion Studies in Contemporary Neuroscience.Trends in cognitive sciences · 2019Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Anxiety disorders are characterized by excessive attention to threat. Several brain areas, including the orbitofrontal cortex (OFC), have been associated with threat processing, with more recent work implicating specialized roles for the medial and lateral subregions of the OFC in mediating specific symptoms of anxiety disorders. Virtually no causal work, however, has evaluated the role of these OFC subregions in regulating behavioral responses under threat. To address this gap, we compared male rhesus monkeys (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.