Evidence map›Paper›PMID 30910758›Full record

ArticleThe Journal of investigative dermatology2019

Genome-Wide Association Study in Irradiated Childhood Cancer Survivors Identifies HTR2A for Subsequent Basal Cell Carcinoma.

Yadav Sapkota, Lucie M Turcotte, Matthew J Ehrhardt, Rebecca M Howell, Michael A Arnold, Carmen L Wilson, Wendy Leisenring, Zhaoming Wang, Joshua Sampson, Casey L Dagnall and 17 more

Abstract readLetter
In one paragraph

Article in The Journal of investigative dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  12. Genome-wide Association Studies Reveal Novel Locus With Sex-/Therapy-Specific Fracture Risk Effects in Childhood Cancer Survivors.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Yadav SapkotaDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. Electronic address: Yadav.Sapkota@stjude.org.
Lucie M TurcotteDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Matthew J EhrhardtDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Rebecca M HowellDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Michael A ArnoldDepartment of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA; Department of Pathology, The Ohio State University, Columbus, Ohio, USA.
Carmen L WilsonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Wendy LeisenringClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Zhaoming WangDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Joshua SampsonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Casey L DagnallDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Eric KarlinsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Shengchao Alfred LiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Belynda D HicksDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA; Cancer Genomics Research Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Rita WeathersDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Susan A SmithDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Kyla SheltonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Qi LiuSchool of Public Health, University of Alberta, Alberta, Canada.
Margaret A TuckerDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Stephen J ChanockDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Jinghui ZhangDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Melissa M HudsonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Joseph P NegliaDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Gregory T ArmstrongDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Leslie L RobisonDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Lindsay M MortonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Smita BhatiaInstitute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Yutaka YasuiDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, Tennessee, USA; School of Public Health, University of Alberta, Alberta, Canada.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
Mach-LETSGO: Machine-LEarning of Treatment, Survey, and Genetics towards Obtaining Correct Classification of Chronic Conditions in Adult Survivors in the Childhood Cancer Survivor Study - CCSS SupplU24CA055727 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Gregory Armstrong · 1999 to 2026
$96.7M
Studies of Populations Exposed to Therapeutic Medical Radiation and Other AgentsZIACP010131 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI MORTON, LINDSAY · 2009 to 2025
$81.0M
The St. Jude Lifetime CohortU01CA195547 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HUDSON, MELISSA M, NESS, KIRSTEN KIMBERLIE · 2015 to 2024
$14.9M
Late Effects Prediction using Clinical Phenotypes and Whole Genome SequencingR01CA216354 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI YASUI, YUTAKA, ZHANG, JINGHUI · 2017 to 2021
$3.4M
Treatment Modifications, Outcomes and Provider Decision Making in the Management of Subsequent Breast Cancers Among Survivors of Childhood CancerK08CA234232 · NCI · UNIVERSITY OF MINNESOTA · PI TURCOTTE, LUCIE MARIE · 2018 to 2021
$714k
NCI NIH HHS K08 CA234232NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA216354NCI NIH HHS U01 CA195547NCI NIH HHS U24 CA055727
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultBasal Cell CarcinomaCancer SurvivorsChildChild, PreschoolFemaleFollow-Up StudiesGenetic LociGenome-Wide Association StudyHumansLinkage DisequilibriumMaleMiddle AgedNeoplasmsNeoplasms, Radiation-InducedHTR2A protein, humanReceptor, Serotonin, 5-HT2A

Identifiers

PMID30910758
PMCPMC6708785

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.