Evidence map›Paper›PMID 30910420›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2019

Exercise and Cognitive Training as a Strategy to Improve Neurocognitive Outcomes in Heart Failure: A Pilot Study.

Rebecca A Gary, Sudeshna Paul, Elizabeth Corwin, Brittany Butts, Andrew H Miller, Kenneth Hepburn, Bryan Williams, Drenna Waldrop-Valverde

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
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  20. Exercise and Cognitive Training Intervention Improves Self-Care, Quality of Life and Functional Capacity in Persons With Heart Failure.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Rebecca A GaryEmory University Nell Hodgson Woodruff School of Nursing (RAG, SP, EC, BB, KH, BW, DWV), Atlanta. Electronic address: ragary@emory.edu.
Sudeshna PaulEmory University Nell Hodgson Woodruff School of Nursing (RAG, SP, EC, BB, KH, BW, DWV), Atlanta.
Elizabeth CorwinEmory University Nell Hodgson Woodruff School of Nursing (RAG, SP, EC, BB, KH, BW, DWV), Atlanta.
Brittany ButtsEmory University Nell Hodgson Woodruff School of Nursing (RAG, SP, EC, BB, KH, BW, DWV), Atlanta.
Andrew H MillerEmory University School of Medicine (AHM), Winship Cancer Institute, Atlanta.
Kenneth HepburnEmory University Nell Hodgson Woodruff School of Nursing (RAG, SP, EC, BB, KH, BW, DWV), Atlanta.
Bryan WilliamsEmory University Nell Hodgson Woodruff School of Nursing (RAG, SP, EC, BB, KH, BW, DWV), Atlanta.
Drenna Waldrop-ValverdeEmory University Nell Hodgson Woodruff School of Nursing (RAG, SP, EC, BB, KH, BW, DWV), Atlanta.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Atlanta Clinical and Translational Science Institute (KL2)KL2RR025009 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$2.9M
The Center for Cognition and Affect in Chronic IllnessP30NR014134 · NINR · EMORY UNIVERSITY · PI WALDROP, DRENNA · 2012 to 2016
$2.2M
NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR002378NCRR NIH HHS KL2 RR025009NINR NIH HHS P30 NR014134
6 · The paper itself

Abstract

objectiveMild cognitive impairment, especially memory loss, is prevalent in patients with heart failure (HF) and contributes to poor clinical outcomes and higher mortality.

methodsThis study evaluated a combined aerobic exercise and cognitive training (EX/CT) program on memory, executive function, attention, processing speed and reaction time compared to exercise only or a usual care attention control (UCAC) stretching and flexibility program. Participants completed a standardized neurocognitive battery at baseline, 3 months, and 6 months along with demographic, clinical, and functional capacity (6-minute walk test). A linear mixed model analysis was used with comorbidity as a covariate.

resultsSixty-nine participants were enrolled, the mean age was 61 ± 10 years, 54% were women, 55% were African American, and the mean left ventricular ejection fraction percentage was 35 ± 15. A significant group by time interaction for verbal memory was found at 3 months (F [2, 53] = 4.3, p = 0.018) but was not sustained at 6 months in the EX/CT group. Processing speed/attention differed across treatment groups between baseline and 6 months, but improvement occurred among UCAC participants. There were also significant group differences in the 6MWT distance occurring at 3 months (F [2, 52] = 3.5, p = 0.036); however, significant improvement was observed within the EX/CT group only. There were no significant differences in 6MWT in the other groups at 3 or 6 months.

conclusionAn EX/CT intervention was associated with improved memory in persons with HF and warrants further investigation in a larger trial. The relationship between functional capacity and cognitive function also needs further study.

Indexed as

Cognitive RemediationExercise TherapyOutcome Assessment, Health CareAgedAttentionCognitive DysfunctionCombined Modality TherapyExecutive FunctionFemaleFollow-Up StudiesHeart FailureHumansMaleMemory DisordersMiddle AgedPilot Projectscognitive trainingexerciseHeart failuremild cognitive impairment

Identifiers

PMID30910420
PMCPMC6646088

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.