Evidence map›Paper›PMID 30909919›Full record

ArticleLipids in health and disease2019

Sex difference in the incidence of stroke and its corresponding influence factors: results from a follow-up 8.4 years of rural China hypertensive prospective cohort study.

Yali Wang, Yue Dai, Jia Zheng, Yanxia Xie, Rongrong Guo, Xiaofan Guo, Guozhe Sun, Zhaoqing Sun, Yingxian Sun, Liqiang Zheng

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The burden of ischemic stroke and its attributable risk factors among people aged 15-49 years in Asia, 1990-2021: results from the global burden of disease study 2021.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  14. [Incidence and risk factors of ischemic stroke in patients with type 2 diabetes among urban workers in Beijing, China].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yali WangDepartment of Clinical Epidemiology, Library, Department of Health Policy and Hospital Management, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China.
Yue DaiDepartment of Clinical Epidemiology, Library, Department of Health Policy and Hospital Management, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China.
Jia ZhengDepartment of Clinical Epidemiology, Library, Department of Health Policy and Hospital Management, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China.
Yanxia XieDepartment of Clinical Epidemiology, Library, Department of Health Policy and Hospital Management, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China.
Rongrong GuoDepartment of Clinical Epidemiology, Library, Department of Health Policy and Hospital Management, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China.
Xiaofan GuoDepartment of Cardiology, the First Affiliated Hospital of China Medical University, Shenyang, 110001, People's Republic of China.
Guozhe SunDepartment of Cardiology, the First Affiliated Hospital of China Medical University, Shenyang, 110001, People's Republic of China.
Zhaoqing SunDepartment of Cardiology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, Shenyang, 110004, People's Republic of China.
Yingxian SunDepartment of Cardiology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, Shenyang, 110004, People's Republic of China. sunyingxian12@126.com.
Liqiang ZhengDepartment of Clinical Epidemiology, Library, Department of Health Policy and Hospital Management, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China. liqiangzheng@126.com.ORCID http://orcid.org/0000-0003-0101-9398
China Medical University · CN

Funding

National Key R&D Program of China Grant #2017YFC1307600National Nature Science Foundation of China No. 81773510Nature Science Foundation of Liaoning Province No. 20170541048
6 · The paper itself

Abstract

backgroundFew studies investigate sex difference in stroke incidence in rural China hypertensive population.

methodsA total of 5097 hypertensive patients aged ≥35 years (mean age, 56.3 ± 11.2 years; 43.8% men) were included in our analysis with a median follow-up 8.4 years in Fuxin county of Liaoning province in China. Cox proportional hazard models were used to analyze the association between the potential factors and incident stroke.

resultsWe observed 501 new strokes (310 ischemic, 186 hemorrhagic, and 5 unclassified stroke) during the follow-up. The overall incidence of stroke was 1235.21 per 100,000 person-years; for men, the rates were 1652.51 and 920.80 for women. This sex difference in all stroke can be explained by approximately 25% through age, systolic blood pressure, body mass index, low-density lipoprotein-cholesterol, current smoking, current drinking, antihypertensive drugs, education and physical activity. Subgroup analysis indicated that in hemorrhagic stroke this sex difference was more remarkable (63.89% can be explained).

conclusionsThe incidence of stroke was higher in men than that in women and this difference was partly explained by several traditional cardiovascular risk factors.

Indexed as

Blood PressureSex CharacteristicsAdultAgedAlcohol DrinkingAntihypertensive AgentsBody Mass IndexChinaFemaleHumansHypertensionMaleMiddle AgedRisk FactorsRural PopulationStrokeAntihypertensive AgentsIncidenceInfluence factorsSex differenceStroke

Identifiers

PMID30909919
PMCPMC6434616
OpenAlexW2940547134

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.