ArticleBMC genomics2019
Map-based cloning and characterization of BoCCD4, a gene responsible for white/yellow petal color in B. oleracea.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 49 citations in OpenAlex.
- Metabolome and transcriptome integration provide insights into petal color variation of Chrysanthemum indicum.BMC plant biology · 2026Article
- Identification ofPlants (Basel, Switzerland) · 2026Article
- Beyond yellow: discovery and genetic dissection of an apricot petal color inFrontiers in plant science · 2026Article
- Preliminary Analysis of the Formation Mechanism of Floret Color in Broccoli (Plants (Basel, Switzerland) · 2025Article
- Differential expression of CCD4(4B) drives natural variation in fruit carotenoid content in strawberry (Fragaria spp.).Plant biotechnology journal · 2025Article
- Two large inversions seriously suppress recombination and are essential for key genotype fixation in cabbage (Horticulture research · 2024Article
- Map-based cloning and functional analysis of a major quantitative trait locus, BolC.Pb9.1, controlling clubroot resistance in a wild Brassica relative (Brassica macrocarpa).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- The formation and evolution of flower coloration inFrontiers in genetics · 2024Review
- Genetic dissection of morphological variation between cauliflower and a rapid cycling Brassica oleracea line.G3 (Bethesda, Md.) · 2023Article
- A natural mutation in the promoter of Ms-cd1 causes dominant male sterility in Brassica oleracea.Nature communications · 2023Article
- The mechanism of white flower formation in Brassica rapa is distinct from that in other Brassica species.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Recent Advancements and Biotechnological Implications of Carotenoid Metabolism ofPlants (Basel, Switzerland) · 2023Review
- Transcriptome Analysis Reveals Key Genes and Pathways Associated with the Petal Color Formation in Cabbage (International journal of molecular sciences · 2022Article
- The Carotenoid Esterification GeneFrontiers in plant science · 2022Article
- Map-Based Cloning and Characterization ofFrontiers in plant science · 2022Article
- Site-Directed Mutagenesis of the Carotenoid Isomerase GeneFrontiers in plant science · 2022Article
- Genetic mapping and candidate gene identification of BoGL5, a gene essential for cuticular wax biosynthesis in broccoli.BMC genomics · 2021Article
- Genome-wide characterization and analysis of the anthocyanin biosynthetic genes in Brassica oleracea.Planta · 2021Article
- Exploring the Diversity and Regulation of Apocarotenoid Metabolic Pathways in Plants.Frontiers in plant science · 2021Review
- Fine Mapping and Candidate Gene Identification of a White Flower GeneFrontiers in plant science · 2021Article
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundBrassica oleracea exhibits extensive phenotypic diversity. As an important trait, petal color varies among different B. oleracea cultivars, enabling the study of the genetic basis of this trait. In a previous study, the gene responsible for petal color in B. oleracea was mapped to a 503-kb region on chromosome 3, but the candidate gene has not yet been identified.
resultsIn the present study, we report that the candidate gene was further delineated to a 207-kb fragment. BoCCD4, a homolog of the Arabidopsis carotenoid cleavage dioxygenase 4 (CCD4) gene, was selected for evaluation as the candidate gene. Sequence analysis of the YL-1 inbred line revealed three insertions/deletions and 34 single-nucleotide polymorphisms in the coding region of BoCCD4. Functional complementation showed that BoCCD4 from the white-petal inbred line 11-192 can rescue the yellow-petal trait of YL-1. Expression analysis revealed that BoCCD4 is exclusively expressed in petal tissue of white-petal plants, and phylogenetic analysis indicated that CCD4 homologs may share evolutionarily conserved roles in carotenoid metabolism. These findings demonstrate that BoCCD4 is responsible for white/yellow petal color variation in B. oleracea.
conclusionsThis study demonstrated that function loss of BoCCD4, a homolog of Arabidopsis CCD4, is responsible for yellow petal color in B. oleracea.
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