SynthesisOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2019
Depression in Patients with Tinnitus: A Systematic Review.
Synthesis in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
76 citing papers in PubMed, 3 syntheses or guidelines pooled it, 161 citations in OpenAlex.
- ESR Essentials: diagnostic strategies in tinnitus-practice recommendations by the European Society of Head and Neck Radiology.European radiology · 2025Guideline
- Correlation Between Chronic Tinnitus Distress and Symptoms of Depression: A Systematic Review.Frontiers in neurology · 2022Pooled it
- Efficacy and safety of stellate ganglion block for tinnitus: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Altered parietal multisensory integration in chronic tinnitus during closed-loop real-time fMRI auditory downregulation.NeuroImage. Clinical · 2026Trial
- Comparative Analysis of the Efficacy of Transcutaneous Electrical Nerve Stimulation in Somatic and Idiopathic Tinnitus Patients.Brain and behavior · 2025Trial
- Internet-based cognitive behavioural therapy for tinnitus in Spanish: a global feasibility trial.International journal of audiology · 2022Trial
- Internet-Based Audiologist-Guided Cognitive Behavioral Therapy for Tinnitus: Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- Increased prevalence of depressive symptoms and stress in patients with chronic bothersome tinnitus during the COVID-19 pandemic.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Association between hypertension status and severity and tinnitus: a cross-sectional analysis of the Fasa adult cohort study.BMJ open · 2026Article
- Interactive Effects of Occupational Hearing Loss and Glutathion S-Transferase M1 Genotype on Tinnitus Among Noise-exposed Steelworkers.Safety and health at work · 2026Article
- Impact of Education, Sex, and Residence on Tinnitus Distress, Depression, and Anxiety.Audiology research · 2026Article
- Tinnitus.Nature reviews. Disease primers · 2026Review
- Psychiatric Comorbidity in Chronic Tinnitus: Depression and Anxiety in an Otolaryngology Outpatient Cohort.Neuropsychiatric disease and treatment · 2026Article
- An ICF-based content analysis of the overlap between questionnaires assessing tinnitus distress and depressive symptoms.PloS one · 2026Article
- Cognitive impairment in idiopathic intracranial hypertension: A conceptual framework and therapeutic implications.Surgical neurology international · 2026Review
- More than just noise: Association of pulsatile tinnitus with anxiety, depression, and reduction of quality of life.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- When the Mind Meets the Ear: A Scoping Review on Tinnitus and Clinically Measured Psychiatric Comorbidities.Journal of clinical medicine · 2025Review
- Development and Psychometric Validation of Tinnitus Qualities and Impact Questionnaire.Clinics and practice · 2025Article
- Identifying psychological and clinical risk factors for moderate-to-severe tinnitus in older patients with hearing loss: a multivariable prediction model.Frontiers in neurology · 2025Article
- Development and comparison of machine learning models for predicting moderate-to-severe tinnitus in patients with hearing loss.Frontiers in neurology · 2025Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTinnitus is a condition that causes distress and impairment across cognitive, functional, and psychiatric spectra. In the psychiatric realm, tinnitus has long been associated with depression. To better characterize the co-occurrence of depression and tinnitus, we performed a systematic review of the prevalence of depression among patients with tinnitus. DATA SOURCES: We comprehensively examined original studies reporting the prevalence of depression in adult populations with tinnitus, as indexed in the PubMed and Web of Science databases and published from January 2006 to August 2016. REVIEW
methodsAll identified articles were reviewed independently by 2 researchers, with a third reviewer for adjudication. Included studies were evaluated for threats to validity across 3 domains-representativeness, response rate, and ascertainment of outcome-on a 4-point modified Newcastle-Ottawa Quality Assessment Scale.
resultsTwenty-eight studies were included, representing 15 countries and 9979 patients with tinnitus. Among the included studies, the median prevalence of depression was 33%, with an interquartile range of 19% to 49% and an overall range of 6% to 84%. Studies were high quality overall, with a mean score of 3.3 (SD = 0.76), and 89% utilized a validated tool to ascertain depression.
conclusionsWe conducted one of the largest contemporary comprehensive reviews, which suggests a 33% prevalence of depression among patients with tinnitus. Our review reaffirms that a substantial proportion of patients with tinnitus have depression, and we recommend that all who treat tinnitus should screen and treat their patients for depression, if present.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.