Evidence map›Paper›PMID 30909795›Full record

ArticleJournal of neurotrauma2019

Divergent Six Month Functional Recovery Trajectories and Predictors after Traumatic Brain Injury: Novel Insights from the Citicoline Brain Injury Treatment Trial Study.

Raquel C Gardner, Jing Cheng, Adam R Ferguson, Ross Boylan, John Boscardin, Ross D Zafonte, Geoffrey T Manley, Citicoline Brain Injury Treatment Trial Investigators

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Raquel C GardnerDepartment of Neurology, Memory and Aging Center, and Weill Institute for Neurosciences, University of California, San Franscisco, San Francisco, California.
Jing ChengDeparment of Epidemiology and Biostatistics, University of California, San Francisco, California.
Adam R FergusonDepartment of Neurological Surgery and Weil Institute for Neurosciences, University of California San Francisco, San Francisco, California.
Ross BoylanDeparment of Epidemiology and Biostatistics, University of California, San Francisco, California.
John BoscardinDeparment of Epidemiology and Biostatistics, University of California, San Francisco, California.
Ross D ZafonteDepartment of Physical Medicine and Rehabilitation, Harvard Medical School and Spaulding Rehabilitation Hospital, Boston, Massachusetts.
Geoffrey T ManleyDepartment of Neurological Surgery and Weil Institute for Neurosciences, University of California San Francisco, San Francisco, California.
Citicoline Brain Injury Treatment Trial Investigators
Harvard University · USSan Francisco General Hospital · USSan Francisco VA Medical Center · USUniversity of California, San Francisco · US

Funding

Transforming Research and Clinical Knowledge in Traumatic Brain InjuryU01NS086090 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DIAZ-ARRASTIA, RAMON, GIACINO, JOSEPH THOMAS · 2013 to 2017
$19.1M
Traumatic Brain Injury Clinical Trials Network-DCCU01HD042823 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FRIEDEWALD, WILLIAM T · 2002 to 2011
$10.0M
Traumatic Brain Injury Clinical Trials NetworkU01HD042689 · NICHD · VIRGINIA COMMONWEALTH UNIVERSITY · PI WARD, JOHN D · 2002 to 2010
$3.0M
Traumatic Brain Injury Clinical Trials NetworkU01HD042652 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI DIAZ-ARRASTIA, RAMON · 2003 to 2012
$2.8M
Traumatic Brain Injury Clinical Trials NetworkU01HD042653 · NICHD · UNIVERSITY OF WASHINGTON · PI TEMKIN, NANCY R · 2002 to 2011
$2.5M
Traumatic Brain Injury Clinical Trials NetworkU01HD042678 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RICKER, JOSEPH H · 2002 to 2010
$2.3M
Traumatic Brain Injury Clinical Trials NetworkU01HD042738 · NICHD · TEMPLE UNIV OF THE COMMONWEALTH · PI LOFTUS, CHRISTOPHER · 2002 to 2010
$2.0M
Traumatic Brain Injury Clinical Trials NetworkU01HD042687 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI NOVACK, THOMAS · 2002 to 2010
$1.9M
Traumatic Brain Injury Clinical Trials NetworkU01HD042736 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI EISENBERG, HOWARD M. · 2003 to 2010
$1.8M
Traumatic Brain Injury Clinical Trials NetworkU01HD042686 · NICHD · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI TIMMONS, SHELLY D · 2003 to 2010
$1.6M
Traumatic Brain Injury and The Aging Brain: Predictors of Clinical TrajectoriesK23NS095755 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARDNER, RAQUEL C. · 2015 to 2019
$872k
NICHD NIH HHS U01 HD042652NICHD NIH HHS U01 HD042653NICHD NIH HHS U01 HD042678NICHD NIH HHS U01 HD042686NICHD NIH HHS U01 HD042687NICHD NIH HHS U01 HD042689NICHD NIH HHS U01 HD042736NICHD NIH HHS U01 HD042738NICHD NIH HHS U01 HD042823NINDS NIH HHS K23 NS095755NINDS NIH HHS U01 NS086090
6 · The paper itself

Abstract

Cross-sectional approaches to outcome assessment may not adequately capture heterogeneity in recovery after traumatic brain injury (TBI). Using latent class mixed models (LCMM), a data-driven analytic that identifies groups of patients with similar trajectories, we identified distinct 6 month functional recovery trajectories in a large cohort (

Indexed as

Recovery of FunctionBrain Injuries, TraumaticClinical Trials, Phase III as TopicCohort StudiesCytidine Diphosphate CholineData ScienceDouble-Blind MethodHumansLongitudinal StudiesNootropic AgentsRandomized Controlled Trials as TopicRetrospective StudiesCytidine Diphosphate CholineNootropic Agentsfunctional outcomepredictorsTBItrajectory

Identifiers

PMID30909795
PMCPMC6709728
OpenAlexW2924073792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.