Evidence map›Paper›PMID 30909651›Full record

ArticleJournal of clinical medicine2019

Epigenetic Changes at the

Aleksander Mika, Sarah E Luelling, Adriene Pavek, Christopher Nartker, Alexandra L Heyneman, Kevin B Jones, Jared J Barrott

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Aleksander MikaDepartments of Orthopedics and Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. Aleksander_Mika@urmc.rochester.edu.ORCID 0000-0002-5260-4506
Sarah E LuellingDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA. luelsara@isu.edu.
Adriene PavekDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA. paveadri@isu.edu.
Christopher NartkerDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA. nartchri@isu.edu.
Alexandra L HeynemanDepartment of Biomedical and Pharmaceutical Sciences, Idaho State University, Pocatello, ID 83209, USA. heynalex@isu.edu.
Kevin B JonesDepartments of Orthopedics and Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. kevin.jones@hci.utah.edu.
Jared J BarrottDepartments of Orthopedics and Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT 84112, USA. barrjare@isu.edu.ORCID 0000-0001-6059-9009
Idaho State University · USUniversity of Utah · US

Funding

Targeting SS18-SSX biology in synovial sarcomagenesisU54CA231652 · NCI · UNIVERSITY OF UTAH · PI JONES, KEVIN BRUCE · 2018 to 2022
$12.0M
Epigenetic Mechanisms Driving Synovial SarcomagenesisR01CA201396 · NCI · UNIVERSITY OF UTAH · PI CAIRNS, BRADLEY R., JONES, KEVIN BRUCE · 2017 to 2021
$1.7M
Alex's Lemonade Stand Foundation for Childhood Cancer POSTIdaho State Board of Education Career Path InternshipsIdaho State University Seed grantNCI NIH HHS R01 CA201396NCI NIH HHS R01CA201396NCI NIH HHS U54 CA231652Paul Nabil Bustany Memorial Fund for Synovial Sarcoma Research Research grant
6 · The paper itself

Abstract

YM155 is an anti-cancer therapy that has advanced into 11 different human clinical trials to treat various cancers. This apoptosis-inducing therapy indirectly affects the protein levels of survivin (gene:

Indexed as

Birc5epigeneticssurvivinsynovial sarcomaYM155

Identifiers

PMID30909651
PMCPMC6463023
OpenAlexW2924422638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.