Evidence map›Paper›PMID 30909634›Full record

ArticleInternational journal of molecular sciences2019

Transcriptome Analysis Reveals Cotton (

Mingge Han, Xuke Lu, John Yu, Xiugui Chen, Xiaoge Wang, Waqar Afzal Malik, Junjuan Wang, Delong Wang, Shuai Wang, Lixue Guo and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Annexins: central regulators of plant growth and stress signaling.Acta biochimica et biophysica Sinica · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mingge HanInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. h13707663917@163.com.
Xuke LuInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. 15824990556@163.com.
John YuUSDA-ARS Southern Plains Agricultural Research Center, College Station, TX 77845, USA. john.yu@ars.usda.gov.
Xiugui ChenInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. pycxg-007@163.com.
Xiaoge WangInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. wangxiaoge1990@126.com.
Waqar Afzal MalikInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. Waqarviqi244@gmail.com.
Junjuan WangInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. Wjj2004liyuan@sina.com.
Delong WangInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. wdl_21@126.com.
Shuai WangInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. wangshuai_19871201@163.com.
Lixue GuoInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. guolixue0114@163.com.
Chao ChenInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. cc1218@163.com.
Ruifeng CuiInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. xiaocui0126@126.com.
Xiaoming YangInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. xmyang152@163.com.
Wuwei YeInstitute of Cotton Research of Chinese Academy of Agricultural Science, State Key Laboratory of Cotton Biology, Key Laboratory for Cotton Genetic Improvement, Anyang 455000, Henan, China. yew158@163.com.ORCID 0000-0002-1801-0800

Funding

National Key Research and Development Program 2016YFD0101401USDA-ARS Project 3091-21000-044-01-N
6 · The paper itself

Abstract

High concentrations of heavy metals in the soil should be removed for environmental safety. Cadmium (Cd) is a heavy metal that pollutes the soil when its concentration exceeds 3.4 mg/kg. Although the potential use of cotton to remediate heavy Cd-polluted soils is known, little is understood about the molecular mechanisms of Cd tolerance. In this study, transcriptome analysis was used to identify Cd tolerance genes and their potential mechanisms in cotton. We exposed cotton plants to excess Cd and identified 4627 differentially expressed genes (DEGs) in the root, 3022 DEGs in the stem and 3854 DEGs in the leaves through RNA-Seq analysis. Among these genes were heavy metal transporter coding genes (ABC, CDF, HMA, etc.), annexin genes and heat shock genes (HSP), amongst others. Gene ontology (GO) analysis showed that the DEGs were mainly involved in the oxidation⁻reduction process and metal ion binding. The DEGs were mainly enriched in two pathways, the influenza A and pyruvate pathway. GhHMAD5, a protein containing a heavy-metal binding domain, was identified in the pathway to transport or to detoxify heavy metal ions. We constructed a

Indexed as

Gene Expression Regulation, PlantStress, PhysiologicalAdaptation, BiologicalArabidopsisCadmiumComputational BiologyGene Expression ProfilingGene SilencingGossypiumPhenotypePlant ProteinsPlants, Genetically ModifiedTranscriptomeCadmiumPlant ProteinsCd stresscotton (Gossypium hirsutum L.)GhHMAD5overexpressiontranscriptomeVIGS (virus induced gene silence)

Identifiers

PMID30909634
PMCPMC6470502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.