ArticleNanomaterials (Basel, Switzerland)2019
Real-Time Monitoring of Biotinylated Molecules Detection Dynamics in Nanoporous Anodic Alumina for Bio-Sensing.
Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 43 citations in OpenAlex.
- Real-Time Detection of Human Growth Hormone Based on Nanoporous Anodic Alumina Interferometric Biosensor.Sensors (Basel, Switzerland) · 2025Article
- Sensing Platform Based on Gold Nanoclusters and Nanoporous Anodic Alumina for Preeclampsia Detection.Biosensors · 2024Article
- A Comprehensive Study of Aluminum Anodization in Transition Modes.Materials (Basel, Switzerland) · 2024Article
- Cerium oxide nanoparticles-assisted aptasensor for chronic myeloid leukaemia detection.ADMET & DMPK · 2024Article
- A Novel Biosensing Approach: Improving SnSAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Amplified EQCM-D detection of extracellular vesicles using 2D gold nanostructured arrays fabricated by block copolymer self-assembly.Nanoscale horizons · 2023Article
- Low-Power Negative-Differential-Resistance Device for Sensing the Selective Protein via Supporter Molecule Engineering.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Silica Inverse Opal Nanostructured Sensors for Enhanced Immunodetection of Extracellular Vesicles by Quartz Crystal Microbalance with Dissipation Monitoring.ACS applied nano materials · 2022Article
- Immobilization of Streptavidin on a Plasmonic Au-TiONanomaterials (Basel, Switzerland) · 2022Article
- Double Narrow Fano Resonances via Diffraction Coupling of Magnetic Plasmon Resonances in Embedded 3D Metamaterials for High-Quality Sensing.Nanomaterials (Basel, Switzerland) · 2021Article
- Pronounced Linewidth Narrowing of Vertical Metallic Split-Ring Resonators via Strong Coupling with Metal Surface.Nanomaterials (Basel, Switzerland) · 2021Article
- Recent Advances in Nanoporous Anodic Alumina: Principles, Engineering, and Applications.Nanomaterials (Basel, Switzerland) · 2021Review
- Advances in Optical Biosensors and Sensors Using Nanoporous Anodic Alumina.Sensors (Basel, Switzerland) · 2020Review
- Critical assessment of relevant methods in the field of biosensors with direct optical detection based on fibers and waveguides using plasmonic, resonance, and interference effects.Analytical and bioanalytical chemistry · 2020Review
- An optical biosensor for the determination of cathepsin B as a cancer-associated enzyme using nanoporous anodic alumina modified with human serum albumin-thionine.Mikrochimica acta · 2020Article
- Remote biosensor for the determination of trypsin by using nanoporous anodic alumina as a three-dimensional nanostructured material.Scientific reports · 2020Article
- Aptamer-Based Nanoporous Anodic Alumina Interferometric Biosensor for Real-Time Thrombin Detection.Sensors (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The chemical modification, or functionalization, of the surfaces of nanomaterials is a key step to achieve biosensors with the best sensitivity and selectivity. The surface modification of biosensors usually comprises several modification steps that have to be optimized. Real-time monitoring of all the reactions taking place during such modification steps can be a highly helpful tool for optimization. In this work, we propose nanoporous anodic alumina (NAA) functionalized with the streptavidin-biotin complex as a platform towards label-free biosensors. Using reflective interferometric spectroscopy (RIfS), the streptavidin-biotin complex formation, using biotinylated thrombin as a molecule model, was monitored in real-time. The study compared the performance of different NAA pore sizes in order to achieve the highest response. Furthermore, the optimal streptavidin concentration that enabled the efficient detection of the biotinylated thrombin attachment was estimated. Finally, the ability of the NAA-RIfS system to quantify the concentration of biotinylated thrombin was evaluated. This study provides an optimized characterization method to monitor the chemical reactions that take place during the biotinylated molecules attachment within the NAA pores.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.