Evidence map›Paper›PMID 30909556›Full record

ReviewMolecules (Basel, Switzerland)2019

Natural Products and Obesity: A Focus on the Regulation of Mitotic Clonal Expansion during Adipogenesis.

Eugene Chang, Choon Young Kim

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 168 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Effect of StandardizedNutrients · 2022
    Trial
  4. Article
  5. Article
  6. Article
  7. Adipogenesis Under Leptin Control: Mechanisms and Model-Specific Effects.International journal of molecular sciences · 2026
    Review
  8. Anti-Adipogenic Effects ofInternational journal of molecular sciences · 2026
    Article
  9. Review
  10. Article
  11. International journal of medical sciences · 2026
    Article
  12. Article
  13. International journal of molecular sciences · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Anti‑obesity and immunostimulatory activity ofExperimental and therapeutic medicine · 2024
    Article
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Eugene ChangDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea. eugenics77@hotmail.com.
Choon Young KimDepartment of Food and Nutrition, Yeungnam University, Gyeongsan 38541, Gyeongbuk, Korea. cykim@yu.ac.kr.ORCID 0000-0002-5980-4578
Ewha Womans University · KRYeungnam University · KR

Funding

Yeungnam University the 2016 Yeungnam University Research Grant
6 · The paper itself

Abstract

Obesity is recognized as a worldwide health crisis. Obesity and its associated health complications such as diabetes, dyslipidemia, hypertension, and cardiovascular diseases impose a big social and economic burden. In an effort to identify safe, efficient, and long-term effective methods to treat obesity, various natural products with potential for inhibiting adipogenesis were revealed. This review aimed to discuss the molecular mechanisms underlying adipogenesis and the inhibitory effects of various phytochemicals, including those from natural sources, on the early stage of adipogenesis. We discuss key steps (proliferation and cell cycle) and their regulators (cell-cycle regulator, transcription factors, and intracellular signaling pathways) at the early stage of adipocyte differentiation as the mechanisms responsible for obesity.

Indexed as

AdipocytesAdipogenesisBiological ProductsCell CycleCell DifferentiationHumansMitosisObesitySignal TransductionBiological Products3T3-L1 preadipocytesadipocyte differentiationadipogenesisnatural productsobesity

Identifiers

PMID30909556
PMCPMC6471203
OpenAlexW2924199431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.