Evidence map›Paper›PMID 30909459›Full record

ReviewCancers2019

The Role of MicroRNAs in Hepatoblastoma Tumors.

Ion Cristóbal, Marta Sanz-Álvarez, Melani Luque, Cristina Caramés, Federico Rojo, Jesús García-Foncillas

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  15. Article
  16. A MicroRNA Cluster in theFrontiers in oncology · 2020
    Article
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  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ion CristóbalCancer Unit for Research on Novel Therapeutic Targets, Oncohealth Institute, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, Spain. ion.cristobal@fjd.es.
Marta Sanz-ÁlvarezPathology Department, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, Spain. marta.sanza@quironsalud.es.
Melani LuquePathology Department, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, Spain. melani.luque@quironsalud.es.
Cristina CaramésCancer Unit for Research on Novel Therapeutic Targets, Oncohealth Institute, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, Spain. ccarames@fjd.es.ORCID 0000-0002-5748-7628
Federico RojoPathology Department, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, Spain. frojo@fjd.es.
Jesús García-FoncillasTranslational Oncology Division, Oncohealth Institute, IIS-Fundación Jiménez Díaz-UAM, E-28040 Madrid, Spain. jesus.garciafoncillas@oncohealth.eu.
Hospital Universitario Fundación Jiménez Díaz · ES

Funding

Instituto de Salud Carlos III PI15/00934Instituto de Salud Carlos III PI16/01468
6 · The paper itself

Abstract

Hepatoblastoma is the most common hepatic malignancy during childhood. However, little is still known about the molecular mechanisms that govern the development of this disease. This review is focused on the recent advances regarding the study of microRNAs in hepatoblastoma and their substantial contribution to improv our knowledge of the pathogenesis of this disease. We show here that miRNAs represent valuable tools to identify signaling pathways involved in hepatoblastoma progression as well as useful biomarkers and novel molecular targets to develop alternative therapeutic strategies in this disease.

Indexed as

biomarkershepatoblastomamicroRNAsignalingtherapy

Identifiers

PMID30909459
PMCPMC6468899
OpenAlexW2925202220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.