Evidence map›Paper›PMID 30909380›Full record

ArticleMarine drugs2019

Phytoene Accumulation in the Novel Microalga

Kelly Laje, Mark Seger, Barry Dungan, Peter Cooke, Juergen Polle, F Omar Holguin

Abstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Performance Evaluation ofBioengineering (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Chloroplast Genome and Description ofPlants (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Research of Fluridone's Effects on Growth and Pigment Accumulation ofInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelly LajeDepartment of Plant and Environmental Sciences, New Mexico State University, Las Cruces, NM 88003, USA. klaje@nmsu.edu.
Mark SegerAzCATI, School of Sustainable Engineering and the Built Environment, Arizona State University, Mesa, AZ 85212, USA. mseger1@asu.edu.ORCID 0000-0003-0665-8260
Barry DunganDepartment of Plant and Environmental Sciences, New Mexico State University, Las Cruces, NM 88003, USA. bdungan@nmsu.edu.
Peter CookeCore University Research Resources Laboratory, New Mexico State Univesrity, Las Cruces, NM 88003, USA. phcooke@nmsu.edu.
Juergen PolleDepartment of Biology, Brooklyn College of the City University of New York, Brooklyn, NY 11210, USA. JPolle@brooklyn.cuny.edu.
F Omar HolguinDepartment of Plant and Environmental Sciences, New Mexico State University, Las Cruces, NM 88003, USA. frholgui@nmsu.edu.

Funding

National Institutes of Health R25GM061222National Science Foundation IIA-1301346
6 · The paper itself

Abstract

Carotenoids are lipophilic pigments found in plants and algae, as well as some bacteria, archaea, and fungi that serve two functions-(1) as light harvesting molecules-primary carotenoids, and (2) as antioxidants, acting against reactive oxygen species⁻secondary carotenoids. Because of their strong antioxidant properties, they are also valuable for the development of anti-aging and photo-protective cosmetic applications. Of particular interest is the carotenoid phytoene, for its colorless and UV absorption characteristics. In this study, we targeted a reduction of phytoene desaturase (PDS) activity with the pigment-inhibiting herbicide 1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4-one (fluridone), which leads to the over-accumulation of phytoene in the recently characterized microalgal strain

Indexed as

CarotenoidsChlorophyceaeFatty AcidsOxidoreductasesPyridones(all-E) phytoeneCarotenoidsFatty AcidsfluridoneOxidoreductasesphytoene dehydrogenasePyridonesantioxidantscarotenoidscosmeceuticalsfluridonemicroalgaephytoene

Identifiers

PMID30909380
PMCPMC6471924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.