Evidence map›Paper›PMID 30909324›Full record

ArticleAging cell2019

NMNAT2-mediated NAD

Xinghan Wu, Feifei Hu, Juan Zeng, Longsen Han, Danhong Qiu, Haichao Wang, Juan Ge, Xiaoyan Ying, Qiang Wang

Open access · goldAbstract read
In one paragraph

Article in Aging cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 102 citations in OpenAlex.

  1. Review
  2. NMN Can Restore Ovarian Reserve in Aged Mice by Upregulating NADReproductive sciences (Thousand Oaks, Calif.) · 2026
    Article
  3. Article
  4. Reverse Effects of Nicotinamide Mononucleotide Supplementation on Declining Quality of Oocytes With Polycystic Ovary Syndrome.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. NADAging and disease · 2024
    Article
  11. Article
  12. Review
  13. Review
  14. Can Nicotinamide Adenine Dinucleotide (NADAnimals : an open access journal from MDPI · 2024
    Review
  15. NADTheranostics · 2024
    Article
  16. Article
  17. Review
  18. Impact of NAD+ metabolism on ovarian aging.Immunity & ageing : I & A · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xinghan WuState Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Feifei HuDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Juan ZengState Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Longsen HanState Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Danhong QiuState Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Haichao WangState Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Juan GeState Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.
Xiaoyan YingDepartment of Obstetrics and Gynecology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qiang WangState Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, China.ORCID 0000-0003-0000-9139
Nanjing Medical University · CNSecond Affiliated Hospital of Nanjing Medical University · CN

Funding

Health Department Project of Jiangsu Province F201513National Key Research and Development Program 2017YFC1001500National Key Research and Development Program 2018YFC1004000National Natural Science Foundation 31571543National Natural Science Foundation 31771657Science Foundation for Distinguished Young Scholars of Jiangsu Province BK20180035
6 · The paper itself

Abstract

Advanced maternal age has been reported to impair oocyte quality; however, the underlying mechanisms remain to be explored. In the present study, we identified the lowered NAD

Indexed as

AgingAnimalsChromosomesFemaleMaternal AgeMeiosisMiceMice, Inbred ICRMice, TransgenicNADNicotinamide-Nucleotide AdenylyltransferaseOocytesOxidation-ReductionOxidative StressReactive Oxygen SpeciesSirtuin 1NADNicotinamide-Nucleotide AdenylyltransferaseNmnat2 protein, mouseReactive Oxygen SpeciesSirtuin 1maternal agemeiosismetabolismoocyte qualityoxidative stress

Identifiers

PMID30909324
PMCPMC6516161
OpenAlexW2946174795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.