ArticlePloS one2019
Snakin-1 affects reactive oxygen species and ascorbic acid levels and hormone balance in potato.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 45 citations in OpenAlex.
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- Pangenomic Approach for the Identification and Functional Characterization of Active GASA Antimicrobial Genes in Citrus Rootstocks for Resistance Breeding Against Bacterial Pathogens.Plants (Basel, Switzerland) · 2026Article
- Overexpression of DWF1 Enhances Low-Nitrogen Stress Tolerance in Potato Plants.International journal of molecular sciences · 2025Article
- Plant Defense Peptides: Exploring the Structure-Function Correlation for Potential Applications in Drug Design and Therapeutics.ACS omega · 2025Review
- Functional Analysis of Durum Wheat GASA1 Protein as a Biotechnological Alternative Against Plant Fungal Pathogens and a Positive Regulator of Biotic Stress Defense.Plants (Basel, Switzerland) · 2025Article
- Study on molecular response of alfalfa to low temperature stress based on transcriptomic analysis.BMC plant biology · 2024Article
- Genome-Wide Identification and Characterization of thePlants (Basel, Switzerland) · 2024Article
- The Stylo Cysteine-Rich PeptideInternational journal of molecular sciences · 2024Article
- A GASA Protein Family Gene,International journal of molecular sciences · 2024Article
- Snakins: antimicrobial potential and prospects of genetic engineering for enhanced disease resistance in plants.Molecular biology reports · 2023Review
- GASA Proteins: Review of Their Functions in Plant Environmental Stress Tolerance.Plants (Basel, Switzerland) · 2023Review
- The study on interacting factors and functions of GASA6 in Jatropha curcas L.BMC plant biology · 2023Article
- Growth and transcriptional response of wheat and rice to the tertiary amine BMVE.Frontiers in plant science · 2023Article
- Phenotypes and Endotypes of Peach Allergy: What Is New?Nutrients · 2022Review
- Transcriptional responses to Fusarium oxysporum f. sp. lycopersici (Sacc.) Snyder & Hansen infection in three Colombian tomato cultivars.BMC plant biology · 2021Article
- The Cysteine-Rich Peptide Snakin-2 Negatively Regulates Tubers Sprouting through Modulating Lignin Biosynthesis and HInternational journal of molecular sciences · 2021Article
- State of the Art of Genetic Engineering in Potato: From the First Report to Its Future Potential.Frontiers in plant science · 2021Review
- Molecular and Biological Properties of Snakins: The Foremost Cysteine-Rich Plant Host Defense Peptides.Journal of fungi (Basel, Switzerland) · 2020Review
- Enhancing of anthracnose disease resistance indicates a potential role of antimicrobial peptide genes in cassava.Genetica · 2020Article
- Potato Snakin-1: an antimicrobial player of the trade-off between host defense and development.Plant cell reports · 2020Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Snakin-1 is a member of the Solanum tuberosum Snakin/GASA family. We previously demonstrated that Snakin-1 is involved in plant defense to pathogens as well as in plant growth and development, but its mechanism of action has not been completely elucidated yet. Here, we showed that leaves of Snakin-1 silenced potato transgenic plants exhibited increased levels of reactive oxygen species and significantly reduced content of ascorbic acid. Furthermore, Snakin-1 silencing enhanced salicylic acid content in accordance with an increased expression of SA-inducible PRs genes. Interestingly, gibberellic acid levels were also enhanced and transcriptome analysis revealed that a large number of genes related to sterol biosynthesis were downregulated in these silenced lines. Moreover, we demonstrated that Snakin-1 directly interacts with StDIM/DWF1, an enzyme involved in plant sterols biosynthesis. Additionally, the analysis of the expression pattern of PStSN1::GUS in potato showed that Snakin-1 is present mainly in young tissues associated with active growth and cell division zones. Our comprehensive analysis of Snakin-1 silenced lines demonstrated for the first time in potato that Snakin-1 plays a role in redox balance and participates in a complex crosstalk among different hormones.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.