Evidence map›Paper›PMID 30908927›Full record

ArticleAnnals of the American Thoracic Society2019

Combined Forced Expiratory Volume in 1 Second and Forced Vital Capacity Bronchodilator Response, Exacerbations, and Mortality in Chronic Obstructive Pulmonary Disease.

Spyridon Fortis, Alejandro Comellas, Barry J Make, Craig P Hersh, Sandeep Bodduluri, Dimitris Georgopoulos, Victor Kim, Gerard J Criner, Mark T Dransfield, Surya P Bhatt and 1 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Annals of the American Thoracic Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Predictors of Acute Exacerbations in COPD: A Systematic Review.International journal of chronic obstructive pulmonary disease · 2026
    Pooled it
  2. Trial
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  5. Article
  6. Article
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  10. Prevalence, Diagnostic Utility and Associated Characteristics of Bronchodilator Responsiveness.American journal of respiratory and critical care medicine · 2024
    Article
  11. Article
  12. Review
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  15. Article
  16. Article
  17. Article
  18. The Challenges of Spirometric Diagnosis of COPD.Canadian respiratory journal · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Spyridon Fortis1 Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa Hospital and Clinics, Iowa City, Iowa.ORCID 0000-0001-7807-6740
Alejandro Comellas1 Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa Hospital and Clinics, Iowa City, Iowa.ORCID 0000-0003-1521-7520
Barry J Make3 Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, Colorado.
Craig P Hersh4 Division of Pulmonary and Critical Care Medicine and.ORCID 0000-0002-1342-4334
Sandeep Bodduluri6 UAB Lung Imaging Core, Lung Health Center, Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Dimitris Georgopoulos2 Medical School.
Victor Kim9 Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania; and.
Gerard J Criner9 Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania; and.
Mark T Dransfield6 UAB Lung Imaging Core, Lung Health Center, Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Surya P Bhatt6 UAB Lung Imaging Core, Lung Health Center, Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
COPDGene Investigators–Core Units: <italic>Administrative Center</italic>, COPDGene Investigators–Clinical Centers: <italic>Ann Arbor VA</italic>
University of Alabama at Birmingham · USTemple University · USUniversity of Iowa Hospitals and Clinics · USBrigham and Women's Hospital · USNational Jewish Health · USUniversity of Crete · GR

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Amy Leanne Ryan · 1998 to 2026
$30.5M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
Ultra-low Dose, High Speed, High Resolution, Multispectral, Multi-Source MDCT ScaS10OD018526 · OD · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2015 to 2015
$2.0M
Diastolic Dysfunction and Pauci-inflammatory Acute Exacerbations of Chronic Obstructive Pulmonary DiseaseK23HL133438 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BHATT, SURYA P. · 2016 to 2020
$921k
Clinical significance and genetic determinants of novel imaging measures of emphysema distribution in 9,743 smokersK08HL141601 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI EL BOUEIZ, ADEL · 2018 to 2022
$853k
UAB Mentoring Program in COPD Patient Oriented ResearchK24HL140108 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DRANSFIELD, MARK T · 2018 to 2022
$439k
NHLBI NIH HHS K08 HL141601NHLBI NIH HHS K23 HL133438NHLBI NIH HHS K24 HL140108NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897NIDDK NIH HHS P30 DK054759NIEHS NIH HHS P30 ES005605NIH HHS S10 OD018526
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease ProgressionAgedAsthmaBronchodilator AgentsCohort StudiesFemaleForced Expiratory VolumeHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisProportional Hazards ModelsPulmonary Disease, Chronic ObstructiveRespiratory Function TestsRetrospective StudiesBronchodilator Agentsasthmabronchodilator agentschronic obstructive pulmonary diseasemortalityspirometry

Identifiers

PMID30908927
PMCPMC6600841
OpenAlexW2934087453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.