ArticlePharmacoepidemiology and drug safety2019
The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations.
Article in Pharmacoepidemiology and drug safety, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed.
- Agreement and utility between registry and trial mortality data - a data utility comparison in the BOSS trial.Trials · 2026Trial
- Incidence and prevalence of obstructive sleep apnoea and narcolepsy in the UK: a population-based descriptive study.Thorax · 2026Article
- Observational
- Trends in incidence, prevalence, and survival of primary liver cancer in the United Kingdom (2000-2021).European journal of public health · 2026Article
- Article
- Enhancing evidence-based care using trial emulation in electronic health records: real-world effects of empagliflozin in people with type 2 diabetes.BMJ open diabetes research & care · 2026Article
- Comparative dementia risk with GLP1 receptor agonists, SGLT2 inhibitors, or DPP4 inhibitors: a population-based cohort study.Alzheimer's research & therapy · 2025Article
- Article
- Article
- Long-term kidney outcomes after COVID-19: a matched cohort study using the OpenSAFELY platform.The Lancet regional health. Europe · 2025Article
- Article
- Article
- Clustering of electronic health records in atrial fibrillation patients and impact on prognosis and patient trajectories: a UK linked-dataset study.European heart journal. Digital health · 2025Article
- Data Resource Profile Update: CPRD GOLD.International journal of epidemiology · 2025Article
- Incidence, prevalence, and mortality of sarcoidosis in England: a population-based study.The Lancet regional health. Europe · 2025Article
- Observational
- Piloting a minimum data set for older people living in care homes in England: a developmental study.Age and ageing · 2025Article
- Causes of death in patients with atrial fibrillation in the UK: a nationwide electronic health record study.European heart journal open · 2025Article
- In-silico trials of targeted screening for abdominal aortic aneurysms using linked healthcare data: A study protocol.PloS one · 2025Article
- Delirium risk and mortality in people with pre-existing severe mental illness: a retrospective cohort study using linked datasets in England.Psychological medicine · 2024Article
Corrections and comments
- Commented on by
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIt is not clear whether all deaths are recorded in the Clinical Practice Research Datalink (CPRD) or how accurate a recorded date of death is. Individual-level linkage with national data from the Office for National Statistics (ONS) and Hospital Episode Statistics (HES) in England offers the opportunity to compare death information across different data sources.
methodsAge-standardised mortality rates (ASMRs) standardised to the European Standard Population (ESP) 2013 for CPRD were compared with figures published by the ONS, and crude mortality rates were calculated for a sample population with individual linkage between CPRD, ONS, and HES data. Agreement on the fact of death between CPRD and ONS was assessed and presented over time from 1998 to 2013.
resultsThere were 33 997 patients with a record of death in the ONS data; 33 389 (98.2%) of these were also identified in CPRD. Exact agreement on the death date between CPRD and the ONS was 69.7% across the whole study period, increasing from 53.4% in 1998 to 78.0% in 2013. By 2013, 98.8% of deaths were in agreement within ±30 days.
conclusionsFor censoring follow-up and calculating mortality rates, CPRD data are likely to be sufficient, as a delay in death recording of up to 1 month is unlikely to impact results significantly. Where the exact date of death or the cause is important, it may be advisable to include the individually linked death registration data from the ONS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.