Evidence map›Paper›PMID 30908781›Full record

ReviewMovement disorders : official journal of the Movement Disorder Society2019

Parkinson's disease gene therapy: Will focused ultrasound and nanovectors be the next frontier?

Richard J Price, Delaney G Fisher, Jung Soo Suk, Justin Hanes, Han Seok Ko, Jeffrey H Kordower

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Movement disorders : official journal of the Movement Disorder Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Blood-brain barrier opening with focused ultrasound in experimental models of Parkinson's disease.Movement disorders : official journal of the Movement Disorder Society · 2019
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Richard J PriceDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Delaney G FisherDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Jung Soo SukCenter for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Justin HanesCenter for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Han Seok KoDepartment of Neurology, Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jeffrey H KordowerDepartment of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.

Funding

Immunotherapeutic Nanoparticle Delivery to Melanoma With MR-Guided Focused UltrasoundR01CA197111 · NCI · UNIVERSITY OF VIRGINIA · PI BULLOCK, TIMOTHY N, ENGELHARD, VICTOR H · 2015 to 2019
$2.6M
Innovative systemic gene therapy for treating Parkinson's diseaseR01NS111102 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI PRICE, RICHARD J., SUK, JUNG SOO · 2019 to 2023
$2.6M
MRI-Guided miRNA Nanoparticle Delivery to Glioblastoma With Focused UltrasoundR01EB020147 · NIBIB · UNIVERSITY OF VIRGINIA · PI HANES, JUSTIN S., PRICE, RICHARD J. · 2015 to 2018
$2.4M
NCI NIH HHS R01 CA197111NIBIB NIH HHS R01 EB020147NINDS NIH HHS R01 NS111102
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsExtracorporeal Shockwave TherapyGenetic TherapyGenetic VectorsGene Transfer TechniquesHumansMagnetic Resonance ImagingNanostructuresParkinson Disease

Identifiers

PMID30908781
PMCPMC6754296

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.