Evidence map›Paper›PMID 30908714›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2020

Impact of Gastrostomy Tube Placement on Short-Term Weight Gain in Hospitalized Premature Infants.

Mihai Puia-Dumitrescu, Daniel K Benjamin, P Brian Smith, Rachel G Greenberg, Nada Abuzaid, Winsome Andrews, Kris Chellani, Anjali Gupta, Douglas Price, Ciara Williams and 3 more

Open access · greenAbstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Mihai Puia-DumitrescuDepartment of Pediatrics, University of Washington, Seattle, Washington, USA.
Daniel K BenjaminDepartment of Economics, Clemson University, Clemson, South Carolina, USA.
P Brian SmithDepartment of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
Rachel G GreenbergDepartment of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
Nada AbuzaidDuke Clinical Research Institute, Durham, North Carolina, USA.
Winsome AndrewsDuke Clinical Research Institute, Durham, North Carolina, USA.
Kris ChellaniDuke Clinical Research Institute, Durham, North Carolina, USA.
Anjali GuptaDuke Clinical Research Institute, Durham, North Carolina, USA.
Douglas PriceDuke Clinical Research Institute, Durham, North Carolina, USA.
Ciara WilliamsDuke Clinical Research Institute, Durham, North Carolina, USA.
William F MalcolmDepartment of Pediatrics, University of Washington, Seattle, Washington, USA.
Reese H ClarkPediatrix-Obstetrix Center for Research and Education, Sunrise, Florida, USA.
Kanecia O ZimmermanDepartment of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA.
Clinical Research Institute · USDuke Medical Center · USClemson University · USMednax (United States) · USUniversity of Washington · US

Funding

Duke Research Training Program for PediatriciansT32HD043029 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2002 to 2017
$3.7M
NIH Summer Research Experience Programs (R25)R25HD076475 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2013 to 2023
$1.1M
Investigating polypharmacy-related adverse events in critically ill children using electronic health records and simulated drug levelsK23HD091398 · NICHD · DUKE UNIVERSITY · PI ZIMMERMAN, KANECIA OBIE · 2017 to 2020
$629k
NICHD NIH HHS HHSN275201000003CNICHD NIH HHS HHSN275201000003INICHD NIH HHS K23 HD091398NICHD NIH HHS R25 HD076475NICHD NIH HHS T32 HD043029
6 · The paper itself

Abstract

backgroundGastrostomy tube (G-tube) placement is a long-term alternative to oral or nasogastric feeding for premature infants who cannot safely feed orally or need supplemental nutrition for adequate growth.

methodsWe compared daily weight changes for G-tube infants 14 and 30 days preplacement and postplacement, excluding the first 7 days post-G-tube insertion. Infants <37 weeks of gestation without major congenital anomalies and discharged from 327 United States neonatal intensive care units (2004-2013) were included. Incidence of in-hospital outcomes including hypoxic ischemic encephalopathy, intraventricular hemorrhage grade 3 or 4, necrotizing enterocolitis, and patent ductus arteriosus ligation was examined. Additionally, we estimated a treatment effect model in which infants with a G-tube were matched 1:1 to untreated controls based on propensity scores; main outcome was the average treatment effect (weight gain) for treated infants during the 7, 14, or 30 days immediately prior to discharge.

resultsOf 329,254 infants, 1393 (0.4%) received a G-tube, increasing from 0.2% in 2004 to 0.6% in 2013. Daily weight gain was significantly less during days 8-14 postplacement compared with 14 days preplacement but was similar between 30 days preplacement and 8-30 days postplacement. After matching, G-tube infant weight gain during the 7 days predischarge was less than among controls, but there was no difference in weight gain between treated and control patients for 14 days and 30 days predischarge.

conclusionsThe prevalence of G-tube placement has increased. G-tube use in infants was not associated with improved short-term daily weight gain.

Indexed as

GastrostomyInfant, PrematureWeight GainCesarean SectionEnteral NutritionFemaleHumansInfantInfant, NewbornMalePregnancygastrostomy tubepremature infantsweight gain

Identifiers

PMID30908714
PMCPMC7295029
OpenAlexW2973684134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.