Evidence map›Paper›PMID 30908570›Full record

Trial reportRevista espanola de sanidad penitenciaria

Rapid diagnostic testing to improve access to screening for syphilis in prison.

K Montaño, A Flores, M Villarroel-Torrico, N Cossio, A Salcedo-Meneses, C Valencia-Rivero, R Castro-Soto, G Gétaz-Jiménez, H Wolff, H Bermúdez-Paredes and 1 more

Open access · greenAbstract readClinical TrialComparative Study
PubMed Full text at PMC
In one paragraph

Trial report in Revista espanola de sanidad penitenciaria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

K MontañoLabimed, Universidad Mayor de San Simón, Cochabamba, Bolivia.
A FloresLabimed, Universidad Mayor de San Simón, Cochabamba, Bolivia.
M Villarroel-TorricoUniversidad Mayor de San Simón, Cochabamba, Bolivia.
N CossioUnidad Médica, Régimen Penitenciario, Cochabamba, Bolivia.
A Salcedo-MenesesDirección General de Régimen Penitenciario, Ministerio de Gobierno, La Paz, Bolivia.
C Valencia-RiveroPrograma Nacional ITS/VIH/SIDA/VH, Ministerio de Salud, La Paz, Bolivia.
R Castro-SotoServicio de Enfermedades Infecciosas, Hospital Clínico VIEDMA, Cochabamba, Bolivia.
G Gétaz-JiménezLaboratory of Bacteriology, Department of Genetic and Laboratory Medicine, Geneva University Hospitals, Geneva, Switzerland.
H WolffDivision of Penitentiary Medicine, Geneva University Hospitals and University of Geneva, Switzerland.
H Bermúdez-ParedesLabimed, Universidad Mayor de San Simón, Cochabamba, Bolivia.
L GétazDivision of Penitentiary Medicine, Geneva University Hospitals and University of Geneva, Switzerland.
Ministerio de Salud · BOUniversity Hospital of Geneva · CHUniversity of Geneva · CHUniversity of San Simón · BO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the accuracy of on-site rapid treponemal test for syphilis diagnosis in women deprived of liberty in Bolivia. MATERIAL AND

methodsSerological tests for syphilis were performed on 219 women deprived of liberty from the San Sebastián prison in Cochabamba, Bolivia. Syphilis was diagnosed using RPR (bioMérieux) and TPPA (Fujirebio) serological tests, and the results were compared to on-site rapid treponemal test (Alere DetermineTM Syphilis TP) in whole blood. Diagnostic performance of two FTA tests were also compared (bioMérieux and Biocientífica).

resultsAll participants (28) with RPR+/TPPA+ had the rapid syphilis test positive (sensitivity 100%). Eleven participants had rapid syphilis test positive without RPR and TPPA both positive; nevertheless 7 of them had RPR or TPPA positive. Of 33 participants with FTA-bioMérieux positive, 22 (66.6%) had FTA-Biocientífica positive. DISCUSSION: The rapid syphilis test Determine shows excellent performance as a screening tool among women deprived of liberty affected by high prevalence of syphilis. This test is particularly indicated when there are barriers for access to conventional serological tests. It is inexpensive, easy to use and does not require electricity and laboratory infrastructure. The FTA test performed with reagents from Biocientífica had a suboptimal sensitivity.

Indexed as

Health Services AccessibilityPrisonsReagent Kits, DiagnosticAdultBiomarkersBoliviaCross-Sectional StudiesFemaleHumansMass ScreeningSensitivity and SpecificitySyphilisSyphilis SerodiagnosisBiomarkersReagent Kits, Diagnostic

Identifiers

PMID30908570
PMCPMC6463320
OpenAlexW2906324226

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.