Evidence map›Paper›PMID 30908528›Full record

ArticlePloS one2019

Dengue seroprevalence among asymptomatic blood donors during an epidemic outbreak in Central-West Brazil.

Svetoslav Nanev Slavov, Daiani Cristina Cilião-Alves, Filipe Almeida Carvalho Gonzaga, Drielly Rodrigues Moura, Ana Carolina Alves Melo de Moura, Lorena Aparecida Gonçalves de Noronha, Évelin Mota Cassemiro, Bárbara Maciel Sidou Pimentel, Fabiano José Queiroz Costa, Grasiela Araújo da Silva and 4 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Ocular Manifestations of Flavivirus Infections.Pathogens (Basel, Switzerland) · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Svetoslav Nanev SlavovBlood Center of Ribeirão Preto, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Daiani Cristina Cilião-AlvesEuro-American University Centre - UNIEURO, Brasilia, Federal District, Brazil.
Filipe Almeida Carvalho GonzagaFaculty of Ceilândia, University of Brasilia, Brasilia, Federal District, Brazil.ORCID 0000-0002-3680-4284
Drielly Rodrigues MouraFaculty of Ceilândia, University of Brasilia, Brasilia, Federal District, Brazil.
Ana Carolina Alves Melo de MouraFaculty of Ceilândia, University of Brasilia, Brasilia, Federal District, Brazil.
Lorena Aparecida Gonçalves de NoronhaFaculty of Ceilândia, University of Brasilia, Brasilia, Federal District, Brazil.ORCID 0000-0002-1303-8062
Évelin Mota CassemiroFaculty of Ceilândia, University of Brasilia, Brasilia, Federal District, Brazil.
Bárbara Maciel Sidou PimentelBlood Center of Brasilia, Brasilia, Federal District, Brazil.
Fabiano José Queiroz CostaCentral Public Health Laboratory of Federal District - LACEN-DF, Brasilia, Federal District, Brazil.
Grasiela Araújo da SilvaCentral Public Health Laboratory of Federal District - LACEN-DF, Brasilia, Federal District, Brazil.
Doralina do Amaral Rabello RamosLaboratory of Molecular Pathology of Cancer, Faculty of Health Sciences and Medicine, University of Brasilia, Brasilia, Federal District, Brazil.
Wildo Navegantes de AraújoFaculty of Ceilândia, University of Brasilia, Brasilia, Federal District, Brazil.
Simone KashimaBlood Center of Ribeirão Preto, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Rodrigo HaddadFaculty of Ceilândia, University of Brasilia, Brasilia, Federal District, Brazil.
Universidade de Brasília · BRInstituto Federal de Educação, Ciência e Tecnologia de Brasília · BRUniversidade de São Paulo · BRCentro Universitário Euroamericano · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus (DENV) transmission by blood transfusion is an important route of viral acquisition during outbreaks. The prevalence of DENV markers (viral RNA, NS1, anti-DENV IgM, and IgG) among blood donors in Central-West Brazil has never been evaluated. Our aim was to evaluate the full set of serological and molecular markers for DENV among blood donors of the Federal District of Brazil during an extensive outbreak in 2016. We found an anti-DENV IgM prevalence of 6.74% (n = 32/475). Of 475, 20 samples (4.21%) were also anti-DENV IgG positive. All samples were non-reactive for NS1 and DENV RNA. Our results imply that a significant proportion of the tested donors had experienced asymptomatic infection. More studies are necessary to evaluate the real prevalence of DENV viremia in blood donors from the Federal District of Brazil and if specific measures are needed to routinely test the blood donors for DENV RNA during outbreaks.

Indexed as

Disease OutbreaksAdultAntibodies, ViralAsymptomatic InfectionsBlood DonorsBlood TransfusionBrazilCohort StudiesDengueDengue VirusFemaleHumansImmunoglobulin GImmunoglobulin MMalePilot ProjectsAntibodies, ViralImmunoglobulin GImmunoglobulin MNS1 protein, dengue-1 virusRNA, ViralViral Nonstructural Proteins

Identifiers

PMID30908528
PMCPMC6433220
OpenAlexW2996199462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.