ArticlePloS one2019
Cost-effective and multifunctional acquisition system for in vitro electrophysiological investigations with multi-electrode arrays.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Inkube: an all-in-one solution for neuron culturing, electrophysiology, and fluidic exchange.Lab on a chip · 2026Article
- A Low-Cost Multimodal Testbed for Array-Based Electrophysiological Microelectrodes.Sensors (Basel, Switzerland) · 2025Article
- Novel Approaches to Studying SLC13A5 Disease.Metabolites · 2024Review
- Light-weight electrophysiology hardware and software platform for cloud-based neural recording experiments.Journal of neural engineering · 2021Article
- An Open-Source Wireless Electrophysiological Complex for In Vivo Recording Neuronal Activity in the Rodent's Brain.Sensors (Basel, Switzerland) · 2021Article
- Article
- Noninvasive Multielectrode Array for Brain and Spinal Cord Local Field Potential Recordings from Live Zebrafish Larvae.Zebrafish · 2020Article
- Multi-Electrode Array with a Planar Surface for Cell Patterning by Microprinting.Sensors (Basel, Switzerland) · 2019Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In vitro multi-electrode array (MEA) technology is nowadays involved in a wide range of applications beyond neuroscience, such as cardiac electrophysiology and bio-interface studies. However, the cost of commercially available acquisition systems severely limits its adoption outside specialized laboratories with high budget capabilities. Thus, the availability of low-cost methods to acquire signals from MEAs is important to allow research labs worldwide to exploit this technology for an ever-expanding pool of experiments independently from their economic possibilities. Here, we provide a comprehensive toolset to assemble a multifunctional in vitro MEA acquisition system with a total cost 80% lower than standard commercial solutions. We demonstrate the capabilities of this acquisition system by employing it to i) characterize commercial MEA devices by means of electrical impedance measurements ii) record activity from cultures of HL-1 cells extracellularly, and iii) electroporate HL-1 cells through nanostructured MEAs and record intracellular signals.
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