ReviewClinical and translational gastroenterology2019
Modulatory Effects of Pregnancy on Inflammatory Bowel Disease.
Review in Clinical and translational gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- Phase II, Open-Label Clinical Trial of Urinary-Derived Human Chorionic Gonadotropin/Epidermal Growth Factor for Life-Threatening Acute Graft-versus-Host Disease.Transplantation and cellular therapy · 2023Trial
- Optimizing disease assessment and care pathways for pregnant women with inflammatory bowel disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Successful Pregnancy Outcome in a Patient With Crohn's Disease and Prior Intestinal Surgery: A Case Report.Cureus · 2026Article
- Cutaneous Manifestations and Dermatologic Adverse Events in IBD: A Clinical Update.Inflammatory bowel diseases · 2026Review
- Sex differences in immune modulation: implications for infection, inflammation, and nutritional supplementation.Biology of sex differences · 2026Review
- Pregnancy Outcomes and Disease Activity in Women With Inflammatory Bowel Disease in Qatar: A Retrospective Cohort Study.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Antibody Transfer From Mother to Fetus/Infant: An Opportunity for Model-Informed Precision Medicine.Journal of clinical pharmacology · 2026Article
- Evaluation of zonulin levels in pregnant women with hyperemesis gravidarum.BMC pregnancy and childbirth · 2025Article
- How long is long enough? Timing of pre-conceptional remission predicts relapse risk during pregnancy in IBD.Journal of Crohn's & colitis · 2025Article
- The disease course in microscopic colitis may be influenced by hormonal factors.BMC gastroenterology · 2025Article
- Influence of biological sex in inflammatory bowel diseases.Nature reviews. Gastroenterology & hepatology · 2025Review
- MicroRNA Sequencing of Serum Exosomes Reveals miR205-5p as an Anti-Fibrogenic Factor Against Intestinal Fibrosis in Crohn's Disease.International journal of molecular sciences · 2025Article
- Article
- Selecting first-line advanced therapy for ulcerative colitis: A clinical application of personalized medicine.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024Review
- [Clinical characteristics of pregnancy complicated with inflammatory bowel disease].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024Article
- Case report: Fecal microbiota transplant forFrontiers in immunology · 2024Article
- Associations between sex hormones, receptors, binding proteins and inflammatory bowel disease: a Mendelian randomization study.Frontiers in endocrinology · 2024Article
- Markers of intestinal immune activation and inflammation are not associated with preterm birth among women with low level HIV viremia.American journal of reproductive immunology (New York, N.Y. : 1989) · 2023Article
- Gut Microbiome Changes in Gestational Diabetes.International journal of molecular sciences · 2022Review
- Elevated IL-6 and IL-22 in Early Pregnancy Are Associated with Worse Disease Course in Women with Inflammatory Bowel Disease.International journal of molecular sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The disease course of autoimmune diseases such as rheumatoid arthritis is altered during pregnancy, and a similar modulatory role of pregnancy on inflammatory bowel disease (IBD) has been proposed. Hormonal, immunological, and microbial changes occurring during normal pregnancy may interact with the pathophysiology of IBD. IBD consists of Crohn's disease and ulcerative colitis, and because of genetic, immunological, and microbial differences between these disease entities, they may react differently during pregnancy and should be described separately. This review will address the pregnancy-induced physiological changes and their potential effect on the disease course of ulcerative colitis and Crohn's disease, with emphasis on the modulation of epithelial barrier function and immune profiles by pregnancy hormones, microbial changes, and microchimerism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.