Evidence map›Paper›PMID 30908075›Full record

ReviewImmunohematology2019

Inhibition of blood group antibodies by soluble substances.

Karen M Byrne, Chloe Marie C Mercado, Thaddeus N Nnabue, Traci D Paige, Willy A Flegel

Open access · hybridAbstract readReview
In one paragraph

Review in Immunohematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Application of Saliva Inhibition to Detect Underlying Alloantibodies in Bombay Blood Group.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Karen M ByrneSBB Program Education Coordinator, National Institutes of Health (NIH) Clinical Center, Department of Transfusion Medicine, 10 Center Drive, Bethesda, MD.
Chloe Marie C MercadoReference Technologist, American Red Cross, Pomona, CA.
Thaddeus N NnabueTraining Technologist, Transfusion Medicine, Walter Reed National Military Medical Center.
Traci D PaigeSBB Program Director and Supervisor of Transfusion Services, National Institutes of Health (NIH) Clinical Center, Department of Transfusion Medicine, Bethesda, MD.
Willy A FlegelSBB Program Medical Director, Chief of Laboratory Services Section, National Institutes of Health (NIH) Clinical Center, Department of Transfusion Medicine, Bethesda, MD.
National Institutes of Health Clinical Center · USAmerican Red Cross · USWalter Reed National Military Medical Center · US

Funding

Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

conclusionsThe presence of multiple alloantibodies or an antibody to a highprevalance antigen in a patient sample can pose challenges in antibody identification. The pattern of reactivity seen on an antibody panel may show various strengths of reactivity by different methods of testing or same strength of reactivity at one or more phases of testing. To ensure proper identification, multiple investigative tools may be used. We review one of these methods-inhibition by soluble substances-which has become an expansion of our toolbox within the past 10 years. Alloantibodies can be inhibited using specific soluble substances. These soluble substances occur naturally in various fluids or can be manufactured. When a patient sample contains multiple antibodies, clinically significant or not, inhibition of one may help determine specificities of others. Specific inhibition of a particular antibody will also help to confirm its presence.

Indexed as

AntibodiesBlood Group AntigensHumansIsoantibodiesAntibodiesBlood Group AntigensIsoantibodies

Identifiers

PMID30908075
PMCPMC6436639
OpenAlexW2994839933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.