Evidence map›Paper›PMID 30907013›Full record

SynthesisClinical cardiology2019

Left atrial function in elite athletes: A meta-analysis of two-dimensional speckle tracking echocardiographic studies.

Cesare Cuspidi, Marijana Tadic, Carla Sala, Elisa Gherbesi, Guido Grassi, Giuseppe Mancia

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Atrial cardiomyopathy in endurance athletes.NPJ cardiovascular health · 2024
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  12. Article
  13. Article
  14. Review
  15. Echocardiography and strain analysis in Malaysian elite athletes versus young healthy adults.International journal of cardiology. Heart & vasculature · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Cesare CuspidiDepartment of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Marijana TadicClinical Research Unit, University Clinical Hospital Center "Dr. Dragisa Misovic - Dedinje", Milan, Italy.ORCID https://orcid.org/0000-0002-6235-5152
Carla SalaDepartment of Clinical Sciences and Community Health, University of Milano and Fondazione Ospedale Maggiore IRCCS Policlinico di Milano, Milan, Italy.
Elisa GherbesiDepartment of Clinical Sciences and Community Health, University of Milano and Fondazione Ospedale Maggiore IRCCS Policlinico di Milano, Milan, Italy.
Guido GrassiDepartment of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Giuseppe ManciaDepartment of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
University of Milan · ITIRCCS Istituto Auxologico Italiano · ITMultiMedica · ITUniversity Hospital Center Dr Dragiša Mišović · RSUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe sought to investigate left atrial (LA) volume, function, and strain in elite athletes by a meta-analysis including echocardiographic studies that provided volumetric and strain analysis of LA phasic function.

methodsThe OVID-MEDLINE, PubMed, and Cochrane CENTRAL databases were searched for English-language articles without time restriction up to February 2018 through focused and high sensitive search strategies. Studies were identified by crossing the following search terms: "athletes," "left atrial size," "left atrial volume," "atrial function," "atrial strain," "atrial strain rate," "echocardiography," "2D speckle echocardiography."

resultsMeta-analysis included 403 athletes and 314 active but not trained healthy controls from 9 studies. Pooled data showed that average LA volume index was higher in athletes than in healthy controls (28.0 ± 1.0 vs 20.7 ± 0.8 mL/m

conclusionsOur meta-analysis shows that LA volume is higher, while LA reservoir and contractile functions are impaired in elite athletes during active training compared to untrained controls. Whether these changes persist during deconditioning periods remains to be determined. These alterations may be related to the higher risk of arrhythmias, in particular atrial fibrillation, reported among middle/old aged athletes.

Indexed as

AthletesAtrial Function, LeftAtrial RemodelingCardiomegaly, Exercise-InducedEchocardiographyMyocardial ContractionAdaptation, PhysiologicalAdultBiomechanical PhenomenaFemaleHeart AtriaHumansMaleMiddle AgedPredictive Value of TestsYoung Adultleft atriummeta-analysisphasic functionstrainvolume

Identifiers

PMID30907013
PMCPMC6523010
OpenAlexW2937218885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.