Evidence map›Paper›PMID 30907008›Full record

ArticlePsychophysiology2019

Relation of depression symptoms to sustained reward and loss sensitivity.

Michael P Berry, Ema Tanovic, Jutta Joormann, Charles A Sanislow

Open access · greenAbstract read
In one paragraph

Article in Psychophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  6. Food Inhibitory Control and Reward Responsiveness in Healthy Aging.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
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  16. Using multilevel models for the analysis of event-related potentials.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Michael P BerryA.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts.
Ema TanovicDepartment of Psychology, Yale University, New Haven, Connecticut.
Jutta JoormannDepartment of Psychology, Yale University, New Haven, Connecticut.
Charles A SanislowDepartment of Psychology, Wesleyan University Program in Neuroscience and Behavior, Middletown, Connecticut.
Yale University · USMassachusetts General Hospital · USWesleyan University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Cognitive Control in Borderline &Trauma PsychopathologyK23MH073708 · NIMH · YALE UNIVERSITY · PI SANISLOW, CHARLES A · 2005 to 2010
$885k
NCATS NIH HHS UL1 TR001863NIMH NIH HHS 073708NIMH NIH HHS K23 MH073708
6 · The paper itself

Abstract

Depression is characterized by altered sensitivity to rewards, with recent evidence suggesting that the ability to sustain responses to rewards across long experimental tasks is diminished. Most work on sustained reward responsiveness has taken a categorical approach and focused on major depressive disorder. However, impairments in reward sensitivity are also found at lower levels of symptom severity and may be relevant for understanding basic mechanisms linking reward processing abnormalities to depression. The current study took a dimensional approach to examine the relation between depression symptoms and sustained reward responsiveness by examining how early neural responses to rewards and losses change over a short time course (i.e., during the experiment). In a sample of 45 unselected undergraduates, changes in the amplitude of the reward positivity (RewP) and feedback negativity (FN) were examined over the course of a simple gambling task using multilevel modeling. Amplitude of the RewP was sustained and amplitude of the FN increased during the task. Unlike prior work focused on clinical populations, depression symptoms in this unselected sample were associated with enhanced RewP and FN responding over the course of the task. Results echo prior work that underscores the importance of examining changes in response to reward across trials and further suggests that sustained responses to both rewards and losses vary in relation to symptom level.

Indexed as

AdolescentBrainDepressionElectroencephalographyEvoked PotentialsFemaleHumansMaleNeuropsychological TestsPersonality AssessmentPsychiatric Status Rating ScalesRewardYoung AdultdepressionERPsyoung adults

Identifiers

PMID30907008
PMCPMC6570571
OpenAlexW2943946924

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.