ArticleOphthalmology. Glaucoma
Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye.
Article in Ophthalmology. Glaucoma. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Genetic Aspects of Glaucoma: An Updated Review.Current molecular medicine · 2024Review
- Myocilin misfolding and glaucoma: A 20-year update.Progress in retinal and eye research · 2023Review
- Common and rare myocilin variants: Predicting glaucoma pathogenicity based on genetics, clinical, and laboratory misfolding data.Human mutation · 2021Review
- Molecular Insights into Myocilin and Its Glaucoma-Causing Misfolded Olfactomedin Domain Variants.Accounts of chemical research · 2021Review
- Differential Misfolding Properties of Glaucoma-Associated Olfactomedin Domains from Humans and Mice.Biochemistry · 2019Article
- Juvenile-onset open-angle glaucoma - A clinical and genetic update.Survey of ophthalmologyReview
- Gonioscopy-Assisted Transluminal Trabeculotomy for Myocilin-Associated Juvenile Open-Angle Glaucoma: A Case Series of 8 Eyes Over 2.2 to 4.1 Years.Ophthalmology. GlaucomaArticle
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Objective: Mutations in myocilin ( Design: Case-control, immunohistochemical study of a donor eye from a patient with JOAG caused by a Tyr437His Subjects: An eye from a 59-year-old male with JOAG caused by a Tyr437His Methods: Frozen fixed sections of the iridocorneal angle were prepared from the donor eyes of the Main Outcome Measure: Qualitative comparison of MYOC protein labeling and localization in the trabecular meshwork of donor eyes from a glaucoma patient with a Results: Using immunohistochemistry, we detected more abundant MYOC protein within the trabecular meshwork of the Conclusions: This is the first histopathological analysis of an eye from a glaucoma patient with a
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.