Evidence map›Paper›PMID 30906870›Full record

ArticleScience advances2019

pH-dependent gating mechanism of the

Yanxiang Cui, Kang Zhou, David Strugatsky, Yi Wen, George Sachs, Z Hong Zhou, Keith Munson

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Urease in acetogenicGut microbes · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Unraveling atomic complexity from frozen samples.Structural dynamics (Melville, N.Y.) · 2025
    Article
  7. Protein Structures of Urea Transporters.Sub-cellular biochemistry · 2025
    Review
  8. Review
  9. Article
  10. Microbially Induced Calcium Carbonate Precipitation byApplied and environmental microbiology · 2023
    Review
  11. Application of biomaterials in the eradication ofFrontiers in microbiology · 2023
    Review
  12. Cryo-EM for Small Molecules.Current protocols · 2022
    Review
  13. Review
  14. Urea transport and hydrolysis in the rumen: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021
    Review
  15. Cryo-electron microscopy analysis of small membrane proteins.Current opinion in structural biology · 2020
    Review
  16. Article
  17. Genome organization and interaction with capsid protein in a multipartite RNA virus.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  18. Urea-aromatic interactions in biology.Biophysical reviews · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yanxiang CuiCalifornia NanoSystems Institute, University California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-8909-6576
Kang ZhouCalifornia NanoSystems Institute, University California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-3034-2808
David StrugatskyDepartment of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, CA 90095, USA.
Yi WenDavid Geffen School of Medicine, University of California Los Angeles and Greater West Los Angeles Health Care System, Los Angeles, CA 90095, USA.
George SachsDavid Geffen School of Medicine, University of California Los Angeles and Greater West Los Angeles Health Care System, Los Angeles, CA 90095, USA.
Z Hong ZhouCalifornia NanoSystems Institute, University California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-8373-4717
Keith MunsonDavid Geffen School of Medicine, University of California Los Angeles and Greater West Los Angeles Health Care System, Los Angeles, CA 90095, USA.
California NanoSystems Institute · USVA Greater Los Angeles Healthcare System · USUniversity of California, Los Angeles · US

Funding

Genome Structure, Transcription and Packaging of dsRNA VirusesR01AI094386 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Z Hong ZHOU · 2012 to 2026
$6.0M
High-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0M
In situ atomic structures of the Kaposi's sarcoma-associated herpesvirus portal-terminase complex and glycoproteinsR01DE025567 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WU, TING-TING, ZHOU, Z HONG · 2016 to 2024
$4.0M
West/Midwest Consortium for High-Resolution Cryo Electron MicroscopyU24GM116792 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AGBANDJE-MCKENNA, MAVIS, DOKLAND, TERJE · 2016 to 2020
$3.0M
THE GASTRIC ACID PUMP AS A TARGET FOR ULCER TREATMENTR01DK058333 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SACHS, GEORGE · 2000 to 2009
$2.6M
HIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6M
GASTRIC ENTEROCHROMAFFIN-LIKE CELL IN ULCER DISEASER01DK046917 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SACHS, GEORGE · 1994 to 2005
$798k
Direct Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598k
NCRR NIH HHS S10 RR023057NIAID NIH HHS R01 AI094386NIDCR NIH HHS R01 DE025567NIDDK NIH HHS R01 DK046917NIDDK NIH HHS R01 DK058333NIGMS NIH HHS R01 GM071940NIGMS NIH HHS U24 GM116792NIH HHS S10 OD018111
6 · The paper itself

Abstract

The urea channel of

Indexed as

Bacterial ProteinsCryoelectron MicroscopyHelicobacter InfectionsHelicobacter pyloriHumansHydrogen-Ion ConcentrationMembrane Transport ProteinsProtein ConformationStomach NeoplasmsBacterial ProteinsMembrane Transport ProteinsUreI protein, Helicobacter pylori

Identifiers

PMID30906870
PMCPMC6426461
OpenAlexW2923808424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.