Evidence map›Paper›PMID 30906787›Full record

ArticleJournal of immunology research2019

Comparative Serological Study for the Prevalence of Anti-MERS Coronavirus Antibodies in High- and Low-Risk Groups in Qatar.

Reham A Al Kahlout, Gheyath K Nasrallah, Elmoubasher A Farag, Lingshu Wang, Erik Lattwein, Marcel A Müller, Mohamed E El Zowalaty, Hamad E Al Romaihi, Barney S Graham, Asmaa A Al Thani and 1 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. The incidence of the novel coronavirus SARS-CoV-2 among asymptomatic patients: A systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
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  12. Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Reham A Al Kahlout *Department of Biomedical Sciences, College of Health Sciences, Qatar University, Doha, Qatar.
Gheyath K Nasrallah *Department of Biomedical Sciences, College of Health Sciences, Qatar University, Doha, Qatar.
Elmoubasher A FaragCommunicable Diseases Control Programs, Public Health Department, Ministry of Public Health, Doha, Qatar.
Lingshu WangVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA.
Erik LattweinEuroimmun AG, Luebeck, Germany.
Marcel A MüllerInstitute of Virology, Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.
Mohamed E El ZowalatyVirology and Microbiology Research Laboratory, School of Health Sciences, College of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4000, South Africa.ORCID 0000-0002-1056-4761
Hamad E Al RomaihiCommunicable Diseases Control Programs, Public Health Department, Ministry of Public Health, Doha, Qatar.
Barney S GrahamVaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA.
Asmaa A Al ThaniDepartment of Biomedical Sciences, College of Health Sciences, Qatar University, Doha, Qatar.
Hadi M YassineDepartment of Biomedical Sciences, College of Health Sciences, Qatar University, Doha, Qatar.ORCID 0000-0001-7592-2788
Qatar University · QAMinistry of Public Health · QANational Institute of Allergy and Infectious Diseases · USCharité - Universitätsmedizin Berlin · DEEuroimmun Medizinische Labordiagnostika (Germany) · DEUniversity of KwaZulu-Natal · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) could be asymptomatic or cause mild influenza-like illness. Therefore, the prevalence of MERS-CoV infections in the general population could be underestimated, which necessitates active surveillance to determine the epidemiological importance of asymptomatic cases. The aim of this study is to evaluate the performance of various serological assays and to estimate the seroprevalence of anti-MERS-CoV antibodies in high- and low-risk groups in Qatar. A total of 4858 samples were screened, including 4719 samples collected from healthy blood donors (BD) over a period of five years (2012-2016), 135 samples from baseline case contacts (CC) collected from individuals in close contact with three positive PCR-confirmed patients (CP), and four samples from MERS-CoV CP. Initial screening using anti-MERS-CoV IgG (IgG rS1-ELISA kit) revealed ten reactive samples from BD (10/4719, 0.21%), one from CC (1/135, 0.74%), and three from CP (3/4, 75%). Samples from CP but not from BD were also reactive by whole-virus anti-MERS-CoV IgG (

Indexed as

Population GroupsAdolescentAdultAgedAntibodies, ViralCoronavirus InfectionsCross ReactionsFalse Positive ReactionsFemaleHumansMaleMiddle AgedMiddle East Respiratory Syndrome CoronavirusPrevalenceQatarRiskAntibodies, Viral

Identifiers

PMID30906787
PMCPMC6398027
OpenAlexW2913478568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.